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Title: Systems for the expression of orthogonal translation components eubacterial host cells

Abstract

The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions.

Inventors:
 [1];  [2]
  1. San Diego, CA
  2. La Jolla, CA
Issue Date:
Research Org.:
The Scripps Research Inst., La Jolla, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1055692
Patent Number(s):
8198044
Application Number:
12/224,773
Assignee:
The Scripps Research Institute (La Jolla, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
FG02-03ER46051
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Ryu, Youngha, and Schultz, Peter G. Systems for the expression of orthogonal translation components eubacterial host cells. United States: N. p., 2012. Web.
Ryu, Youngha, & Schultz, Peter G. Systems for the expression of orthogonal translation components eubacterial host cells. United States.
Ryu, Youngha, and Schultz, Peter G. Tue . "Systems for the expression of orthogonal translation components eubacterial host cells". United States. https://www.osti.gov/servlets/purl/1055692.
@article{osti_1055692,
title = {Systems for the expression of orthogonal translation components eubacterial host cells},
author = {Ryu, Youngha and Schultz, Peter G},
abstractNote = {The invention relates to compositions and methods for the in vivo production of polypeptides comprising one or more unnatural amino acids. Specifically, the invention provides plasmid systems for the efficient eubacterial expression of polypeptides comprising one or more unnatural amino acids at genetically-programmed positions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2012},
month = {6}
}

Patent:

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Works referenced in this record:

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