Biosensor method and system based on feature vector extraction
Abstract
A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.
- Inventors:
-
- Knoxville, TN
- (Oak Ridge, TN)
- San Jose, CA
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1040794
- Patent Number(s):
- 8158377
- Application Number:
- 11/216,282
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- AC05-00OR22725
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Greenbaum, Elias, Rodriguez, Jr., Miguel, Qi, Hairong, and Wang, Xiaoling. Biosensor method and system based on feature vector extraction. United States: N. p., 2012.
Web.
Greenbaum, Elias, Rodriguez, Jr., Miguel, Qi, Hairong, & Wang, Xiaoling. Biosensor method and system based on feature vector extraction. United States.
Greenbaum, Elias, Rodriguez, Jr., Miguel, Qi, Hairong, and Wang, Xiaoling. Tue .
"Biosensor method and system based on feature vector extraction". United States. https://www.osti.gov/servlets/purl/1040794.
@article{osti_1040794,
title = {Biosensor method and system based on feature vector extraction},
author = {Greenbaum, Elias and Rodriguez, Jr., Miguel and Qi, Hairong and Wang, Xiaoling},
abstractNote = {A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent biosensor signal from the biosensor in the gas or liquid medium to be monitored or analyzed for the presence of one or more toxins selected from chemical, biological or radiological agents. The time-dependent biosensor signal is processed to obtain a plurality of feature vectors using at least one of amplitude statistics and a time-frequency analysis. At least one parameter relating to toxicity of the gas or liquid medium is then determined from the feature vectors based on reference to the control signal.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 17 00:00:00 EDT 2012},
month = {Tue Apr 17 00:00:00 EDT 2012}
}
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Works referenced in this record:
Development and evaluation of electrochemical glucose enzyme biosensors based on carbon film electrodes
journal, January 2005
- Florescu, M.; Abrett, C.
- Talanta, Vol. 65, Issue 2
Development of infrared optical sensor for selective detection of tyrosine in biological fluids
journal, September 2005
- Huang, Genin Gary; Yang, Jyisy
- Biosensors and Bioelectronics, Vol. 21, Issue 3, p. 408-418
Biosensors for rapid monitoring of primary-source drinking water using naturally occurring photosynthesis
journal, October 2002
- Rodriguez, Miguel; Sanders, Charlene A.; Greenbaum, Elias
- Biosensors and Bioelectronics, Vol. 17, Issue 10, p. 843-849
Magnetic resonance as a technique to magnetic biosensors characterization in Neocapritermes opacus termites
journal, July 2005
- de Oliveira, J. F.; Wajnberg, E.; Esquivel, D. M. S.
- Journal of Magnetism and Magnetic Materials, Vol. 294, Issue 2, p. e171-e174
Acoustic immunosensor for real-time sensing of neurotransmitter GABA
conference, January 2003
- Wang, T.; Muthuswamy, J.
- Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)
Stand-off tissue-based biosensors for the detection of chemical warfare agents using photosynthetic fluorescence induction
journal, September 2001
- Sanders, Charlene A.; Rodriguez, Miguel; Greenbaum, Elias
- Biosensors and Bioelectronics, Vol. 16, Issue 7-8, p. 439-446
Ultrasensitive magnetic biosensor for homogeneous immunoassay
journal, December 2000
- Chemla, Y. R.; Grossman, H. L.; Poon, Y.
- Proceedings of the National Academy of Sciences, Vol. 97, Issue 26