Photochemical tissue bonding

Redmond, Robert W; Kochevar, Irene E

Title: Photochemical tissue bonding

Abstract

Photochemical tissue bonding methods include the application of a photosensitizer to a tissue and/or tissue graft, followed by irradiation with electromagnetic energy to produce a tissue seal. The methods are useful for tissue adhesion, such as in wound closure, tissue grafting, skin grafting, musculoskeletal tissue repair, ligament or tendon repair and corneal repair.

Inventors:

Redmond, Robert W ^[1]; Kochevar, Irene E ^[2]

Brookline, MA
Charlestown, MA

Issue Date:: Tue Jan 10 00:00:00 EST 2012

Research Org.:: The General Hospital Corporation (Boston, MA)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1035048

Patent Number(s):: 8092490

Application Number:: 11/204,958

Assignee:: The General Hospital Corporation (Boston, MA)

Patent Classifications (CPCs):: A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61F - FILTERS IMPLANTABLE INTO BLOOD VESSELS

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A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
A61B2017/005 - {hardenable using external energy source, e.g. laser, ultrasound}
A61B2017/00508 - {using laser}
A61B2017/00517 - {using laser}

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61F - FILTERS IMPLANTABLE INTO BLOOD VESSELS
A61F2009/00853 - {Laser thermal keratoplasty or radial keratotomy}
A61F2009/00872 - {Cornea}
A61F2009/00887 - {Cataract}
A61F9/008 - using laser
A61F9/0081 - {Transplantation}
A61F9/00821 - {for coagulation}

A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61L - METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL
A61L24/001 - {Use of materials characterised by their function or physical properties}
A61L27/50 - Materials characterised by their function or physical properties {, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials}

Show less

DOE Contract Number:: FG02-91ER61228

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 60 APPLIED LIFE SCIENCES

Citation Formats


                    Redmond, Robert W, and Kochevar, Irene E. Photochemical tissue bonding.  United States: N. p., 2012. 
        Web.

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                    Redmond, Robert W, & Kochevar, Irene E. Photochemical tissue bonding.  United States.

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                    Redmond, Robert W, and Kochevar, Irene E. Tue .  
        "Photochemical tissue bonding".  United States.  https://www.osti.gov/servlets/purl/1035048.

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@article{osti_1035048,

  title        = {Photochemical tissue bonding},

  author       = {Redmond, Robert W and Kochevar, Irene E},

  abstractNote = {Photochemical tissue bonding methods include the application of a photosensitizer to a tissue and/or tissue graft, followed by irradiation with electromagnetic energy to produce a tissue seal. The methods are useful for tissue adhesion, such as in wound closure, tissue grafting, skin grafting, musculoskeletal tissue repair, ligament or tendon repair and corneal repair.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Jan 10 00:00:00 EST 2012},

  month        = {Tue Jan 10 00:00:00 EST 2012}

}

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Gene therapy for lung cancer: Enhancement of tumor suppression by a combination of sequential systemic cisplatin and adenovirus-mediated p53 gene transfer
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Studies of RNA Cleavage by Photolysis of N -Hydroxypyridine-2(1 H )-thione. A New Photochemical Footprinting Method ^†
journal, August 2000

Chaulk, Steven G.; Pezacki, John Paul; MacMillan, Andrew M.
Biochemistry, Vol. 39, Issue 34
https://doi.org/10.1021/bi0009136

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Similar Records

Title: Photochemical tissue bonding

Abstract

Citation Formats

Vessel‐wall Recovery after Diode Laser‐Assisted Microvascular Anastomosis: Clinical and Histologic Analysis on Long‐Term Follow‐Up journal, April 1997

Changing Incidence of Achilles Tendon Rupture in Scotland: A 15-Year Study journal, January 1999

Controlled temperature tissue fusion: Argon laser welding of rat intestine in vivo, Part One journal, January 1997

Morphological analysis of microarterial media repair after 830 nm diode laser assisted end-to-end anastomosis: Comparison with conventional manual suture journal, December 1997

p53 is required for radiation-induced apoptosis in mouse thymocytes journal, April 1993

Review of tissue welding applications in neurosurgery journal, January 1987

Tissues and bone adhesives—historical aspects journal, August 1998

N-hydroxy-2-pyridinethione: A mild and convenient source of hydroxyl radicals journal, January 1990

Photodynamic Action: From Paramecium to Photochemotherapy* journal, May 1997

The utilization of a biological adhesive for wound treatment: Comparison of suture, self-sealing sutureless and cyanoacrylate closure in the tensile strength test journal, January 1997

New trends in photobiology bactericidal effects of photoactivated porphyrins — An alternative approach to antimicrobial drugs journal, May 1990

Methylene blue (Methylthionine) Vital Staining of the Cornea and Conjunctiva journal, June 1967

Clinical dose-regimen studies with latanoprost, a new ocular hypotensive PGF2α analogue journal, February 1997

A randomized trial comparing octylcyanoacrylate tissue adhesive and sutures in the management of lacerations journal, May 1997

Photochemistry of the Nonspecific Hydroxyl Radical Generator, N -Hydroxypyridine-2(1 H )-thione journal, January 1996

Newer techniques in intracorporeal tissue approximation: Suturing, tissue adhesives, and microclips journal, February 2001

Quantitative comparison of excited state properties and intensity-dependent photosensitization by rose bengal journal, May 1996

Thermal and infrared-diode laser effects on indocyanine-green-treated corneal collagen conference, July 1993

Relative strength of photodynamic biologic tissue glue in penetrating keratoplasty in cadaver eyes journal, January 1998

Targeted Antimicrobial Photochemotherapy journal, October 1998

Photochemical Sealing Improves Outcome Following Peripheral Neurorrhaphy journal, January 2009

Heat-free photochemical tissue welding with 1,8-naphthalimide dyes using visible (420 nm) light conference, July 1993

Patient Tolerance and Ocular Surface Staining Characteristics of Lissamine Green versus Rose Bengal journal, December 1995

Skin closure by Nd: YAG laser welding journal, May 1986

Sutureless and Reduced Suture Anastomosis of Hollow Vessels With Fibrin Glue: A Review journal, January 1999

Histotoxicity of Cyanoacrylate Tissue Adhesives: A Comparative Study journal, May 1990

Temperature-controlled laser photocoagulation of soft tissue: In vivo evaluation using a tissue welding model journal, January 1996

What Is Actually Stained by Rose Bengal? journal, July 1992

Technical frontiers for the vascular surgeon: Laser anastomotic welding and angioscopy-assisted intraluminal instrumentation journal, April 1987

Organic tissue glue in the closure of cataract incisions journal, January 1987

Late complications of tissue glues in aortic surgery journal, June 2000

Organic tissue glue in the closure of cataract incisions in rabbit eyes journal, January 1991

Human albumin solder supplemented with TGF-β1 accelerates healing following laser welded wound closure journal, January 1996

Gel electrophoretic studies of photochemical cross-linking of type I collagen with brominated 1,8-naphthalimide dyes and visible light conference, September 1994

Preparation and Integration of Human Amnion Nerve Conduits Using a Light-Activated Technique journal, January 2009

Photochemical cross-linking of type I collagen with hydrophobic and hydrophilic 1,8-naphthalimide dyes conference, May 1996

Biodegradable polymer film reinforcement of an indocyanine green-doped liquid albumin solder for laser-assisted incision closure journal, January 2000

Fibrin Sealant: A Review of its Use in Surgery and Endoscopy journal, January 1999

Aggregation of Collagen Exposed to uva in the Presence of Riboflavin: a Plausible role of Tyrosine Modification journal, March 1994

Evaluation of photochemical tissue bonding for closure of skin incisions and excisions journal, January 2005

Biochemistry and biomechanics of healing tendon: Part II. effects of combined laser therapy and electrical stimulation journal, January 1998

Absolute Rate Constants for α-Amide Radical Reactions journal, February 1998

Exclusive Free Radical Mechanisms of Cellular Photosensitization journal, September 1998

Diagnostic Tests in the Sicca Syndrome journal, July 1969

Methylene blue sensitized photo-oxidation of collagen fibrils journal, June 1994

Repair of peripheral nerves with the argon laser. A functional and histological evaluation. journal, January 1990

A Prospective Comparison of Octyl Cyanoacrylate Tissue Adhesive (Dermabond) and Suture for the Closure of Excisional Wounds in Children and Adolescents journal, September 2001

Photodynamic biologic tissue glue to enhance corneal wound healing after radial keratotomy journal, January 1997

In vivo Corneal and Conjunctival Epithelial Nuclear Stain journal, January 1985

Novel solid protein solder designs for laser-assisted tissue repair journal, January 2000

Changes in Extracellular Matrix Components After Excimer Laser Photoablation in Rat Cornea journal, September 1999

Intramolecular Homolytic Substitution at Selenium: Synthesis of Novel Selenium-Containing Vitamin E Analogues journal, September 2001

Quantum Yield of Singlet Oxygen Production by Xanthene Derivatives journal, March 1983

Skin Closure with Dye-Enhanced Laser Welding and Fibrinogen journal, January 1991

Temperature-Controlled CO2 Laser Tissue Welding of Ocular Tissues journal, July 1997

Evaluation of the Effect of Lissamine Green and Rose Bengal on Human Corneal Epithelial Cells journal, January 1999

Total Achilles Tendon Rupture: A Review journal, January 1998

Laser photostimulation of collagen production in healing rabbit achilles tendons journal, January 1998

The generation and reactivity of oxygen centered radicals from the photolysis of derivatives of N-hydroxy-2-thiopyridone. journal, January 1991

Successful Preservation of Human Skin by Vitrification journal, January 2000

Interaction Between Rose Bengal and Different Protein Components journal, January 1995

Effects of endogenous absorption in human albumin solder for acute laser wound closure journal, January 1998

Electron Transfer Quenching of the Rose Bengal Triplet State journal, July 1997

Tissue soldering by use of indocyanine green dye-enhanced fibrinogen with the near infrared diode laser journal, May 1990

Quantitative evaluation after arthroscopic anterior cruciate ligament reconstruction: Allograft versus autograft journal, July 1993

Induction of Cross-links in Corneal Tissue journal, January 1998

Mechanism and stereoselectivity of photosensitized oxygen transfer reactions journal, January 1964

Photolysis of N-Hydroxypyridinethiones: A New Source of Hydroxyl Radicals for the Direct Damage of Cell-Free and Cellular DNA journal, May 1996

Percutaneous microcrystalline chitosan application for sealing arterial puncture sites journal, August 1998

The Use of Autologous Fibrin Adhesive in Skin Transplantation journal, January 1992

PHOTOCHEMISTRY OF 2-MERCAFTOPYRIDINES. PART 2. AN EPR AND SPIN-TRAPPING INVESTIGATION USING 2-METHYL-2-NITROSOPROPANE AND aci-NITROMETHANE AS SPIN TRAPS IN AQUEOUS SOLUTIONS journal, November 1994

Two-layer film as a laser soldering biomaterial journal, January 1999

Semi-solid albumin solder improved mechanical properties for laser tissue welding journal, January 2000

Optimal parameters for laser tissue soldering: II. Premixed versus separate dye-solder techniques journal, January 2000

The epidemiology of achilles tendon rupture in a Danish county journal, October 1998

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents journal, September 1993

Achilles Tendon Ruptures Stratified by Age, Race, and Cause of Injury among Active Duty U.S. Military Members journal, December 1999

Vessel‐wall Recovery after Diode Laser‐Assisted Microvascular Anastomosis: Clinical and Histologic Analysis on Long‐Term Follow‐Up
journal, April 1997

Changing Incidence of Achilles Tendon Rupture in Scotland: A 15-Year Study
journal, January 1999

Controlled temperature tissue fusion: Argon laser welding of rat intestine in vivo, Part One
journal, January 1997

Morphological analysis of microarterial media repair after 830 nm diode laser assisted end-to-end anastomosis: Comparison with conventional manual suture
journal, December 1997

p53 is required for radiation-induced apoptosis in mouse thymocytes
journal, April 1993

Review of tissue welding applications in neurosurgery
journal, January 1987

Tissues and bone adhesives—historical aspects
journal, August 1998

N-hydroxy-2-pyridinethione: A mild and convenient source of hydroxyl radicals
journal, January 1990

Photodynamic Action: From Paramecium to Photochemotherapy*
journal, May 1997

The utilization of a biological adhesive for wound treatment: Comparison of suture, self-sealing sutureless and cyanoacrylate closure in the tensile strength test
journal, January 1997

New trends in photobiology bactericidal effects of photoactivated porphyrins — An alternative approach to antimicrobial drugs
journal, May 1990

Methylene blue (Methylthionine) Vital Staining of the Cornea and Conjunctiva
journal, June 1967

Clinical dose-regimen studies with latanoprost, a new ocular hypotensive PGF2α analogue
journal, February 1997

A randomized trial comparing octylcyanoacrylate tissue adhesive and sutures in the management of lacerations
journal, May 1997

Photochemistry of the Nonspecific Hydroxyl Radical Generator, N -Hydroxypyridine-2(1 H )-thione
journal, January 1996

Newer techniques in intracorporeal tissue approximation: Suturing, tissue adhesives, and microclips
journal, February 2001

Quantitative comparison of excited state properties and intensity-dependent photosensitization by rose bengal
journal, May 1996

Thermal and infrared-diode laser effects on indocyanine-green-treated corneal collagen
conference, July 1993

Relative strength of photodynamic biologic tissue glue in penetrating keratoplasty in cadaver eyes
journal, January 1998

Targeted Antimicrobial Photochemotherapy
journal, October 1998

Photochemical Sealing Improves Outcome Following Peripheral Neurorrhaphy
journal, January 2009

Heat-free photochemical tissue welding with 1,8-naphthalimide dyes using visible (420 nm) light
conference, July 1993

Patient Tolerance and Ocular Surface Staining Characteristics of Lissamine Green versus Rose Bengal
journal, December 1995

Skin closure by Nd: YAG laser welding
journal, May 1986

Sutureless and Reduced Suture Anastomosis of Hollow Vessels With Fibrin Glue: A Review
journal, January 1999

Histotoxicity of Cyanoacrylate Tissue Adhesives: A Comparative Study
journal, May 1990

Temperature-controlled laser photocoagulation of soft tissue: In vivo evaluation using a tissue welding model
journal, January 1996

What Is Actually Stained by Rose Bengal?
journal, July 1992

Technical frontiers for the vascular surgeon: Laser anastomotic welding and angioscopy-assisted intraluminal instrumentation
journal, April 1987

Organic tissue glue in the closure of cataract incisions
journal, January 1987

Late complications of tissue glues in aortic surgery
journal, June 2000

Organic tissue glue in the closure of cataract incisions in rabbit eyes
journal, January 1991

Human albumin solder supplemented with TGF-β1 accelerates healing following laser welded wound closure
journal, January 1996

Gel electrophoretic studies of photochemical cross-linking of type I collagen with brominated 1,8-naphthalimide dyes and visible light
conference, September 1994

Preparation and Integration of Human Amnion Nerve Conduits Using a Light-Activated Technique
journal, January 2009

Photochemical cross-linking of type I collagen with hydrophobic and hydrophilic 1,8-naphthalimide dyes
conference, May 1996

Biodegradable polymer film reinforcement of an indocyanine green-doped liquid albumin solder for laser-assisted incision closure
journal, January 2000

Fibrin Sealant: A Review of its Use in Surgery and Endoscopy
journal, January 1999

Aggregation of Collagen Exposed to uva in the Presence of Riboflavin: a Plausible role of Tyrosine Modification
journal, March 1994

Evaluation of photochemical tissue bonding for closure of skin incisions and excisions
journal, January 2005

Biochemistry and biomechanics of healing tendon: Part II. effects of combined laser therapy and electrical stimulation
journal, January 1998

Absolute Rate Constants for α-Amide Radical Reactions
journal, February 1998

Exclusive Free Radical Mechanisms of Cellular Photosensitization
journal, September 1998

Diagnostic Tests in the Sicca Syndrome
journal, July 1969

Methylene blue sensitized photo-oxidation of collagen fibrils
journal, June 1994

Repair of peripheral nerves with the argon laser. A functional and histological evaluation.
journal, January 1990

A Prospective Comparison of Octyl Cyanoacrylate Tissue Adhesive (Dermabond) and Suture for the Closure of Excisional Wounds in Children and Adolescents
journal, September 2001

Photodynamic biologic tissue glue to enhance corneal wound healing after radial keratotomy
journal, January 1997

In vivo Corneal and Conjunctival Epithelial Nuclear Stain
journal, January 1985

Novel solid protein solder designs for laser-assisted tissue repair
journal, January 2000

Changes in Extracellular Matrix Components After Excimer Laser Photoablation in Rat Cornea
journal, September 1999

Intramolecular Homolytic Substitution at Selenium: Synthesis of Novel Selenium-Containing Vitamin E Analogues
journal, September 2001

Quantum Yield of Singlet Oxygen Production by Xanthene Derivatives
journal, March 1983

Skin Closure with Dye-Enhanced Laser Welding and Fibrinogen
journal, January 1991

Temperature-Controlled CO2 Laser Tissue Welding of Ocular Tissues
journal, July 1997

Evaluation of the Effect of Lissamine Green and Rose Bengal on Human Corneal Epithelial Cells
journal, January 1999

Total Achilles Tendon Rupture: A Review
journal, January 1998

Laser photostimulation of collagen production in healing rabbit achilles tendons
journal, January 1998

The generation and reactivity of oxygen centered radicals from the photolysis of derivatives of N-hydroxy-2-thiopyridone.
journal, January 1991

Successful Preservation of Human Skin by Vitrification
journal, January 2000

Interaction Between Rose Bengal and Different Protein Components
journal, January 1995

Effects of endogenous absorption in human albumin solder for acute laser wound closure
journal, January 1998

Electron Transfer Quenching of the Rose Bengal Triplet State
journal, July 1997

Tissue soldering by use of indocyanine green dye-enhanced fibrinogen with the near infrared diode laser
journal, May 1990

Quantitative evaluation after arthroscopic anterior cruciate ligament reconstruction: Allograft versus autograft
journal, July 1993

Induction of Cross-links in Corneal Tissue
journal, January 1998

Mechanism and stereoselectivity of photosensitized oxygen transfer reactions
journal, January 1964

Photolysis of N-Hydroxypyridinethiones: A New Source of Hydroxyl Radicals for the Direct Damage of Cell-Free and Cellular DNA
journal, May 1996

Percutaneous microcrystalline chitosan application for sealing arterial puncture sites
journal, August 1998

The Use of Autologous Fibrin Adhesive in Skin Transplantation
journal, January 1992

PHOTOCHEMISTRY OF 2-MERCAFTOPYRIDINES. PART 2. AN EPR AND SPIN-TRAPPING INVESTIGATION USING 2-METHYL-2-NITROSOPROPANE AND aci-NITROMETHANE AS SPIN TRAPS IN AQUEOUS SOLUTIONS
journal, November 1994

Two-layer film as a laser soldering biomaterial
journal, January 1999

Semi-solid albumin solder improved mechanical properties for laser tissue welding
journal, January 2000

Optimal parameters for laser tissue soldering: II. Premixed versus separate dye-solder techniques
journal, January 2000

The epidemiology of achilles tendon rupture in a Danish county
journal, October 1998

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
journal, September 1993

Achilles Tendon Ruptures Stratified by Age, Race, and Cause of Injury among Active Duty U.S. Military Members
journal, December 1999

Formaldehyde, Formalin, Paraformaldehyde And Glutaraldehyde: What They Are And What They Do
journal, January 2000

Photochemical Sealing of Microsurgical Neurorrhaphy Improves Functional Recovery
journal, August 2006

Photodynamic Biologic Tissue Glue
journal, January 1994