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Title: Genetically modified yeast of the species Issatchenkia orientalis and closely relates species, and fermentation processes using same

Abstract

Cells of the species Issatchenkia orientalis and closely related yeast species are transformed with a vector to introduce an exogenous lactate dehydrogenase gene. The cells produce lactic acid efficiently and are resistant at low pH, high lactate titer conditions.

Inventors:
 [1];  [2];  [3];  [3];  [3];  [4];  [5]
  1. Maple Grove, MN
  2. Highland Ranch, CO
  3. Helsinki, FI
  4. Vantaa, FI
  5. Minneapolis, MN
Issue Date:
Research Org.:
Cargill Inc. (Wayzata, MN)
Sponsoring Org.:
USDOE
OSTI Identifier:
1034912
Patent Number(s):
8097448
Application Number:
11/921,161
Assignee:
Cargill Inc. (Wayzata, MN)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
DOE Contract Number:  
FC07-02ID14349
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Suominen, Pirkko, Aristidou, Aristos, Pentilla, Merja, Ilmen, Marja, Ruohonen, Laura, Koivuranta, Kari, and Roberg-Perez, Kevin. Genetically modified yeast of the species Issatchenkia orientalis and closely relates species, and fermentation processes using same. United States: N. p., 2012. Web.
Suominen, Pirkko, Aristidou, Aristos, Pentilla, Merja, Ilmen, Marja, Ruohonen, Laura, Koivuranta, Kari, & Roberg-Perez, Kevin. Genetically modified yeast of the species Issatchenkia orientalis and closely relates species, and fermentation processes using same. United States.
Suominen, Pirkko, Aristidou, Aristos, Pentilla, Merja, Ilmen, Marja, Ruohonen, Laura, Koivuranta, Kari, and Roberg-Perez, Kevin. Tue . "Genetically modified yeast of the species Issatchenkia orientalis and closely relates species, and fermentation processes using same". United States. https://www.osti.gov/servlets/purl/1034912.
@article{osti_1034912,
title = {Genetically modified yeast of the species Issatchenkia orientalis and closely relates species, and fermentation processes using same},
author = {Suominen, Pirkko and Aristidou, Aristos and Pentilla, Merja and Ilmen, Marja and Ruohonen, Laura and Koivuranta, Kari and Roberg-Perez, Kevin},
abstractNote = {Cells of the species Issatchenkia orientalis and closely related yeast species are transformed with a vector to introduce an exogenous lactate dehydrogenase gene. The cells produce lactic acid efficiently and are resistant at low pH, high lactate titer conditions.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Jan 17 00:00:00 EST 2012},
month = {Tue Jan 17 00:00:00 EST 2012}
}

Works referenced in this record:

Identification and phylogeny of ascomycetous yeasts from analysis of nuclear large subunit (26S) ribosomal DNA partial sequences
journal, January 1998