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Title: Method of treating depression

Abstract

Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depression. ATP-sensitive K.sup.+ channel openers and .beta.-lactam antibiotics are used to enhance glutamate transport and to treat depression-related mood disorders and depressive symptoms.

Inventors:
 [1]
  1. East Patchogue, NY
Issue Date:
Research Org.:
Brookhaven Science Associates, LLC (Upton, NY)
Sponsoring Org.:
USDOE
OSTI Identifier:
1034635
Patent Number(s):
8101600
Application Number:
12/641,968
Assignee:
Brookhaven Science Associates, LLC (Upton, NY)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
DOE Contract Number:  
AC02-98CH10886
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Henn, Fritz. Method of treating depression. United States: N. p., 2012. Web.
Henn, Fritz. Method of treating depression. United States.
Henn, Fritz. Tue . "Method of treating depression". United States. https://www.osti.gov/servlets/purl/1034635.
@article{osti_1034635,
title = {Method of treating depression},
author = {Henn, Fritz},
abstractNote = {Methods for treatment of depression-related mood disorders in mammals, particularly humans are disclosed. The methods of the invention include administration of compounds capable of enhancing glutamate transporter activity in the brain of mammals suffering from depression. ATP-sensitive K.sup.+ channel openers and .beta.-lactam antibiotics are used to enhance glutamate transport and to treat depression-related mood disorders and depressive symptoms.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2012},
month = {1}
}

Works referenced in this record:

Effect of potassium channel modulators in mouse forced swimming test
journal, April 1999