Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins
Abstract
The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.
- Inventors:
-
- Durham, NC
- Los Alamos, NM
- Birmingham, AL
- Hoover, AL
- Alabaster, AL
- Chapel Hill, NC
- Issue Date:
- Research Org.:
- Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1034345
- Patent Number(s):
- 8071107
- Application Number:
- 10/572,638
- Assignee:
- Duke University (Durham, NC); The Regents of the University of California (Oakland, CA); The University of Alabama at Birmingham Research Foundation (Birmingham, AL)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- AC52-06NA25396
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Haynes, Barton F, Gao, Feng, Korber, Bette T, Hahn, Beatrice H, Shaw, George M, Kothe, Denise, Li, Ying Ying, Decker, Julie, and Liao, Hua-Xin. Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins. United States: N. p., 2011.
Web.
Haynes, Barton F, Gao, Feng, Korber, Bette T, Hahn, Beatrice H, Shaw, George M, Kothe, Denise, Li, Ying Ying, Decker, Julie, & Liao, Hua-Xin. Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins. United States.
Haynes, Barton F, Gao, Feng, Korber, Bette T, Hahn, Beatrice H, Shaw, George M, Kothe, Denise, Li, Ying Ying, Decker, Julie, and Liao, Hua-Xin. Tue .
"Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins". United States. https://www.osti.gov/servlets/purl/1034345.
@article{osti_1034345,
title = {Nucleic acids encoding modified human immunodeficiency virus type 1 (HIV-1) group M consensus envelope glycoproteins},
author = {Haynes, Barton F and Gao, Feng and Korber, Bette T and Hahn, Beatrice H and Shaw, George M and Kothe, Denise and Li, Ying Ying and Decker, Julie and Liao, Hua-Xin},
abstractNote = {The present invention relates, in general, to an immunogen and, in particular, to an immunogen for inducing antibodies that neutralizes a wide spectrum of HIV primary isolates and/or to an immunogen that induces a T cell immune response. The invention also relates to a method of inducing anti-HIV antibodies, and/or to a method of inducing a T cell immune response, using such an immunogen. The invention further relates to nucleic acid sequences encoding the present immunogens.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {12}
}
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