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Title: Lossless droplet transfer of droplet-based microfluidic analysis

Abstract

A transfer structure for droplet-based microfluidic analysis is characterized by a first conduit containing a first stream having at least one immiscible droplet of aqueous material and a second conduit containing a second stream comprising an aqueous fluid. The interface between the first conduit and the second conduit can define a plurality of apertures, wherein the apertures are sized to prevent exchange of the first and second streams between conduits while allowing lossless transfer of droplets from the first conduit to the second conduit through contact between the first and second streams.

Inventors:
 [1];  [2];  [3];  [2]
  1. West Richland, WA
  2. Richland, WA
  3. Kennewick, WA
Issue Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1032987
Patent Number(s):
8061187
Application Number:
12/430,490
Assignee:
Battelle Memorial Institute (Richland, WA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
77 NANOSCIENCE AND NANOTECHNOLOGY

Citation Formats

Kelly, Ryan T, Tang, Keqi, Page, Jason S, and Smith, Richard D. Lossless droplet transfer of droplet-based microfluidic analysis. United States: N. p., 2011. Web.
Kelly, Ryan T, Tang, Keqi, Page, Jason S, & Smith, Richard D. Lossless droplet transfer of droplet-based microfluidic analysis. United States.
Kelly, Ryan T, Tang, Keqi, Page, Jason S, and Smith, Richard D. Tue . "Lossless droplet transfer of droplet-based microfluidic analysis". United States. https://www.osti.gov/servlets/purl/1032987.
@article{osti_1032987,
title = {Lossless droplet transfer of droplet-based microfluidic analysis},
author = {Kelly, Ryan T and Tang, Keqi and Page, Jason S and Smith, Richard D},
abstractNote = {A transfer structure for droplet-based microfluidic analysis is characterized by a first conduit containing a first stream having at least one immiscible droplet of aqueous material and a second conduit containing a second stream comprising an aqueous fluid. The interface between the first conduit and the second conduit can define a plurality of apertures, wherein the apertures are sized to prevent exchange of the first and second streams between conduits while allowing lossless transfer of droplets from the first conduit to the second conduit through contact between the first and second streams.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {11}
}

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Works referenced in this record:

Sampling and Electrophoretic Analysis of Segmented Flow Streams Using Virtual Walls in a Microfluidic Device
journal, November 2008


Capillary Electrophoresis Separation in the Presence of an Immiscible Boundary for Droplet Analysis
journal, October 2006