Self-assembly of peptide-amphiphile nanofibers under physiological conditions
Abstract
The present invention provides a method of promoting neuron growth and development by contacting cells with a peptide amphiphile molecule in an aqueous solution in the presence of a metal ion. According to the method, the peptide amphiphile forms a cylindrical micellar nanofiber composed of beta-sheets, which promote neuron growth and development.
- Inventors:
-
- Chicago, IL
- Pearland, TX
- Auburndale, MA
- Issue Date:
- Research Org.:
- Northwestern University (Evanston, IL)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1032878
- Patent Number(s):
- 8063014
- Application Number:
- 12/797,586
- Assignee:
- Northwestern University (Evanston, IL)
- Patent Classifications (CPCs):
-
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- FG02-00ER45810
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Stupp, Samuel I, Hartgerink, Jeffrey D, and Beniash, Elia. Self-assembly of peptide-amphiphile nanofibers under physiological conditions. United States: N. p., 2011.
Web.
Stupp, Samuel I, Hartgerink, Jeffrey D, & Beniash, Elia. Self-assembly of peptide-amphiphile nanofibers under physiological conditions. United States.
Stupp, Samuel I, Hartgerink, Jeffrey D, and Beniash, Elia. Tue .
"Self-assembly of peptide-amphiphile nanofibers under physiological conditions". United States. https://www.osti.gov/servlets/purl/1032878.
@article{osti_1032878,
title = {Self-assembly of peptide-amphiphile nanofibers under physiological conditions},
author = {Stupp, Samuel I and Hartgerink, Jeffrey D and Beniash, Elia},
abstractNote = {The present invention provides a method of promoting neuron growth and development by contacting cells with a peptide amphiphile molecule in an aqueous solution in the presence of a metal ion. According to the method, the peptide amphiphile forms a cylindrical micellar nanofiber composed of beta-sheets, which promote neuron growth and development.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {11}
}
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