Monolithic multinozzle emitters for nanoelectrospray mass spectrometry

Title: Monolithic multinozzle emitters for nanoelectrospray mass spectrometry

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Abstract

Novel and significantly simplified procedures for fabrication of fully integrated nanoelectrospray emitters have been described. For nanofabricated monolithic multinozzle emitters (NM.sup.2 emitters), a bottom up approach using silicon nanowires on a silicon sliver is used. For microfabricated monolithic multinozzle emitters (M.sup.3 emitters), a top down approach using MEMS techniques on silicon wafers is used. The emitters have performance comparable to that of commercially-available silica capillary emitters for nanoelectrospray mass spectrometry.

Inventors:

Wang, Daojing ^[1]; Yang, Peidong ^[2]; Kim, Woong ^[3]; Fan, Rong ^[4]

Daly City, CA
Kensington, CA
Seoul, KR
Pasadena, CA

Issue Date:: 2011-09-20

Research Org.:: Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1027205

Patent Number(s):: 8022361

Application Number:: 12/298,905

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Classifications (CPCs):: B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS

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B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01L - CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
B01L3/5027 - {by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
H01J49/0018 - {Microminiaturised spectrometers, e.g. chip-integrated devices, MicroElectro-Mechanical Systems [MEMS]}

B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
B82Y15/00 - Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors

H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
H01J49/165 - {Electrospray ionisation}

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DOE Contract Number:: AC02-05CH11231

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 47 OTHER INSTRUMENTATION

Citation Formats


                    Wang, Daojing, Yang, Peidong, Kim, Woong, and Fan, Rong. Monolithic multinozzle emitters for nanoelectrospray mass spectrometry.  United States: N. p., 2011. 
        Web.

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                    Wang, Daojing, Yang, Peidong, Kim, Woong, & Fan, Rong. Monolithic multinozzle emitters for nanoelectrospray mass spectrometry.  United States.

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                    Wang, Daojing, Yang, Peidong, Kim, Woong, and Fan, Rong. Tue .  
        "Monolithic multinozzle emitters for nanoelectrospray mass spectrometry".  United States.  https://www.osti.gov/servlets/purl/1027205.

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@article{osti_1027205,

  title        = {Monolithic multinozzle emitters for nanoelectrospray mass spectrometry},

  author       = {Wang, Daojing and Yang, Peidong and Kim, Woong and Fan, Rong},

  abstractNote = {Novel and significantly simplified procedures for fabrication of fully integrated nanoelectrospray emitters have been described. For nanofabricated monolithic multinozzle emitters (NM.sup.2 emitters), a bottom up approach using silicon nanowires on a silicon sliver is used. For microfabricated monolithic multinozzle emitters (M.sup.3 emitters), a top down approach using MEMS techniques on silicon wafers is used. The emitters have performance comparable to that of commercially-available silica capillary emitters for nanoelectrospray mass spectrometry.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2011},

  month        = {9}

}

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