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Title: Capillary electrophoresis systems and methods

Abstract

An embodiment of the invention is directed to a capillary electrophoresis apparatus comprising a plurality of separation micro-channels. A sample loading channel communicates with each of the plurality of separation channels. A driver circuit comprising a plurality of electrodes is configured to induce an electric field across each of the plurality of separation channels sufficient to cause analytes in the samples to migrate along each of the channels. The system further comprises a plurality of detectors configured to detect the analytes.

Inventors:
 [1];  [2];  [2];  [3];  [4];  [2];  [5];  [2];  [6]
+ Show Inventor Affiliations
  1. Hillsboro, OR
  2. Louisville, KY
  3. Georgetown, IN
  4. New Albany, IN
  5. Goshen, KY
  6. Mount Washington, KY
Issue Date:
Research Org.:
University of Louisville Research Foundation, Inc. (Louisville, KY)
Sponsoring Org.:
USDOE
OSTI Identifier:
1026843
Patent Number(s):
7988839
Application Number:
11/524,357
Assignee:
University of Louisville Research Foundation, Inc. (Louisville, KY)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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DOE Contract Number:  
46411101095
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

Dorairaj, Rathissh, Keynton, Robert S, Roussel, Thomas J, Crain, Mark M, Jackson, Douglas J, Walsh, Kevin M, Naber, John F, Baldwin, Richard P, and Franco, Danielle B. Capillary electrophoresis systems and methods. United States: N. p., 2011. Web.
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Dorairaj, Rathissh, Keynton, Robert S, Roussel, Thomas J, Crain, Mark M, Jackson, Douglas J, Walsh, Kevin M, Naber, John F, Baldwin, Richard P, & Franco, Danielle B. Capillary electrophoresis systems and methods. United States.
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Dorairaj, Rathissh, Keynton, Robert S, Roussel, Thomas J, Crain, Mark M, Jackson, Douglas J, Walsh, Kevin M, Naber, John F, Baldwin, Richard P, and Franco, Danielle B. Tue . "Capillary electrophoresis systems and methods". United States. https://www.osti.gov/servlets/purl/1026843.
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@article{osti_1026843,
title = {Capillary electrophoresis systems and methods},
author = {Dorairaj, Rathissh and Keynton, Robert S and Roussel, Thomas J and Crain, Mark M and Jackson, Douglas J and Walsh, Kevin M and Naber, John F and Baldwin, Richard P and Franco, Danielle B},
abstractNote = {An embodiment of the invention is directed to a capillary electrophoresis apparatus comprising a plurality of separation micro-channels. A sample loading channel communicates with each of the plurality of separation channels. A driver circuit comprising a plurality of electrodes is configured to induce an electric field across each of the plurality of separation channels sufficient to cause analytes in the samples to migrate along each of the channels. The system further comprises a plurality of detectors configured to detect the analytes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {8}
}
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Works referenced in this record:

Design and development of microfabricated capillary electrophoresis devices with electrochemical detection
journal, April 2004

Electrochemical detection in capillary electrophoresis with dual-parallel on-capillary electrodes
journal, September 1998

Planar glass chips for capillary electrophoresis: repetitive sample injection, quantitation, and separation efficiency
journal, May 1993

Dual Capillary Electrophoresis Devices with Electrochemical Detection on a Single Platform
conference, January 2005

Integrated electrochemical detection for lab on a chip analytical microsystems
conference, January 2001

  • Pai, R. S.; Roussel, T. J.; Crain, M. M.
  • Proceedings of the Fourteenth Biennial University/Government/Industry Microelectronics Symposium (Cat. No.01CH37197)
  • https://doi.org/10.1109/UGIM.2001.960323

Alternative fabrication methods for capillary electrophoretic device manufacturing
conference, January 2001

  • Conklin, J. A.; Crain, M. M.; Pai, R. S.
  • Proceedings of the Fourteenth Biennial University/Government/Industry Microelectronics Symposium (Cat. No.01CH37197)
  • https://doi.org/10.1109/UGIM.2001.960299

Electroosmotic Pumping and Valveless Control of Fluid Flow within a Manifold of Capillaries on a Glass Chip
journal, October 1994

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