Title: Variant Hypocrea jecorina CBH2 cellulases

Abstract

Described herein are variants of H. jecorina CBH2, a Cel6A enzyme. The present invention provides novel cellobiohydrolases that have altered thermostability.

Inventors:

Aehle, Wolfgang ^[1]; Goedegebuur, Frits ^[1]; Dankmeyer, Lydia ^[1]; Mitchinson, Colin ^[2]; Neefe, Paulien ^[1]; Kelemen, Brad ^[3]; Caldwell, Robert ^[4]; Teunissen, Pauline ^[1]

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+ Show Inventor Affiliations

1. Leiden, NL
2. Half Moon Bay, CA
3. Menlo Park, CA
4. Belmont, CA

Issue Date:

Tue Aug 30 00:00:00 EDT 2011

Research Org.:

Danisco US Inc. (Palo Alto, CA)

Sponsoring Org.:

USDOE

OSTI Identifier:

1023921

Patent Number(s):

8008056

Application Number:

11/317,110

Assignee:

Danisco US Inc. (Palo Alto, CA)

Patent Classifications (CPCs):

C - CHEMISTRY C11 - ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES C11D - DETERGENT COMPOSITIONS

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

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C - CHEMISTRY C11 - ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES C11D - DETERGENT COMPOSITIONS

C11D3/38645 - {containing cellulase}

C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES

C12N9/2437 - {Cellulases

C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {

C12P19/14 - produced by the action of a carbohydrase {

C - CHEMISTRY C12 - BIOCHEMISTRY C12Y - ENZYMES

C12Y302/01091 - Cellulose 1,4-beta-cellobiosidase

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE Y02E - REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION

Y02E50/10 - Biofuels

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DOE Contract Number:  

AC36-99GO10337

Resource Type:

Patent

Country of Publication:

United States

Language:

English

Subject:

59 BASIC BIOLOGICAL SCIENCES