Genetically modified yeast species and fermentation processes using genetically modified yeast
Abstract
Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications', include deletion of non-specific or specific aldose reductase gene(s), deletion of xylitol dehydrogenase gene(s) and/or overexpression of xylulokinase.
- Inventors:
-
- Kingsport, TN
- Helsinki, FI
- Maple Grove, MN
- Cottage Grove, MN
- St. Bonifacius, MN
- Issue Date:
- Research Org.:
- Cargill Inc. (Wayzata, MN)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1020253
- Patent Number(s):
- 7943366
- Application Number:
- 10/554,887
- Assignee:
- Cargill Inc. (Wayzata, MN)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- DOE Contract Number:
- FC07-02ID14349
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Rajgarhia, Vineet, Koivuranta, Kari, Penttila, Merja, Ilmen, Marja, Suominen, Pirkko, Aristidou, Aristos, Miller, Christopher Kenneth, Olson, Stacey, and Ruohonen, Laura. Genetically modified yeast species and fermentation processes using genetically modified yeast. United States: N. p., 2011.
Web.
Rajgarhia, Vineet, Koivuranta, Kari, Penttila, Merja, Ilmen, Marja, Suominen, Pirkko, Aristidou, Aristos, Miller, Christopher Kenneth, Olson, Stacey, & Ruohonen, Laura. Genetically modified yeast species and fermentation processes using genetically modified yeast. United States.
Rajgarhia, Vineet, Koivuranta, Kari, Penttila, Merja, Ilmen, Marja, Suominen, Pirkko, Aristidou, Aristos, Miller, Christopher Kenneth, Olson, Stacey, and Ruohonen, Laura. Tue .
"Genetically modified yeast species and fermentation processes using genetically modified yeast". United States. https://www.osti.gov/servlets/purl/1020253.
@article{osti_1020253,
title = {Genetically modified yeast species and fermentation processes using genetically modified yeast},
author = {Rajgarhia, Vineet and Koivuranta, Kari and Penttila, Merja and Ilmen, Marja and Suominen, Pirkko and Aristidou, Aristos and Miller, Christopher Kenneth and Olson, Stacey and Ruohonen, Laura},
abstractNote = {Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications', include deletion of non-specific or specific aldose reductase gene(s), deletion of xylitol dehydrogenase gene(s) and/or overexpression of xylulokinase.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {5}
}
Works referenced in this record:
Yeast vectors for integration at the HO locus
journal, June 2001
- Voth, W. P.
- Nucleic Acids Research, Vol. 29, Issue 12
Transformation in fungi.
journal, January 1989
- Fincham, J. R.
- Microbiological Reviews, Vol. 53, Issue 1
Molecular and industrial aspects of glucose isomerase.
journal, January 1996
- Bhosale, S. H.; Rao, M. B.; Deshpande, V. V.
- Microbiological reviews, Vol. 60, Issue 2
Xylulokinase Overexpression in Two Strains of Saccharomyces cerevisiae Also Expressing Xylose Reductase and Xylitol Dehydrogenase and Its Effect on Fermentation of Xylose and Lignocellulosic Hydrolysate
journal, September 2001
- Johansson, B.; Christensson, C.; Hobley, T.
- Applied and Environmental Microbiology, Vol. 67, Issue 9
Amino Acid Substitutions in the Yeast Pichia Stipitis Xylitol Dehydrogenase Coenzyme-Binding Domain Affect the Coenzyme Specificity
journal, February 1995
- Metzger, Markus H.; Hollenberg, Cornells P.
- European Journal of Biochemistry, Vol. 228, Issue 1
High-level functional expression of a fungal xylose isomerase: the key to efficient ethanolic fermentation of xylose by ?
journal, October 2003
- Kuyper, M.; Harhangi, H.; Stave, A.
- FEMS Yeast Research, Vol. 4, Issue 1
Deletion of the GRE3 Aldose Reductase Gene and Its Influence on Xylose Metabolism in Recombinant Strains of Saccharomyces cerevisiae Expressing the xylA and XKS1 Genes
journal, December 2001
- Traff, K. L.; Otero Cordero, R. R.; van Zyl, W. H.
- Applied and Environmental Microbiology, Vol. 67, Issue 12