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Title: Genetically modified yeast species and fermentation processes using genetically modified yeast

Abstract

Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications', include deletion of non-specific or specific aldose reductase gene(s), deletion of xylitol dehydrogenase gene(s) and/or overexpression of xylulokinase.

Inventors:
 [1];  [2];  [2];  [2];  [3];  [3];  [4];  [5];  [2]
  1. Kingsport, TN
  2. Helsinki, FI
  3. Maple Grove, MN
  4. Cottage Grove, MN
  5. St. Bonifacius, MN
Issue Date:
Research Org.:
Cargill Inc. (Wayzata, MN)
Sponsoring Org.:
USDOE
OSTI Identifier:
1020253
Patent Number(s):
7,943,366
Application Number:
10/554,887
Assignee:
Cargill Inc. (Wayzata, MN)
DOE Contract Number:  
FC07-02ID14349
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Rajgarhia, Vineet, Koivuranta, Kari, Penttila, Merja, Ilmen, Marja, Suominen, Pirkko, Aristidou, Aristos, Miller, Christopher Kenneth, Olson, Stacey, and Ruohonen, Laura. Genetically modified yeast species and fermentation processes using genetically modified yeast. United States: N. p., 2011. Web.
Rajgarhia, Vineet, Koivuranta, Kari, Penttila, Merja, Ilmen, Marja, Suominen, Pirkko, Aristidou, Aristos, Miller, Christopher Kenneth, Olson, Stacey, & Ruohonen, Laura. Genetically modified yeast species and fermentation processes using genetically modified yeast. United States.
Rajgarhia, Vineet, Koivuranta, Kari, Penttila, Merja, Ilmen, Marja, Suominen, Pirkko, Aristidou, Aristos, Miller, Christopher Kenneth, Olson, Stacey, and Ruohonen, Laura. Tue . "Genetically modified yeast species and fermentation processes using genetically modified yeast". United States. https://www.osti.gov/servlets/purl/1020253.
@article{osti_1020253,
title = {Genetically modified yeast species and fermentation processes using genetically modified yeast},
author = {Rajgarhia, Vineet and Koivuranta, Kari and Penttila, Merja and Ilmen, Marja and Suominen, Pirkko and Aristidou, Aristos and Miller, Christopher Kenneth and Olson, Stacey and Ruohonen, Laura},
abstractNote = {Yeast cells are transformed with an exogenous xylose isomerase gene. Additional genetic modifications enhance the ability of the transformed cells to ferment xylose to ethanol or other desired fermentation products. Those modifications', include deletion of non-specific or specific aldose reductase gene(s), deletion of xylitol dehydrogenase gene(s) and/or overexpression of xylulokinase.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {5}
}

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Works referenced in this record:

Yeast vectors for integration at the HO locus
journal, June 2001


Transformation in fungi.
journal, January 1989


Molecular and industrial aspects of glucose isomerase.
journal, January 1996


Amino Acid Substitutions in the Yeast Pichia Stipitis Xylitol Dehydrogenase Coenzyme-Binding Domain Affect the Coenzyme Specificity
journal, February 1995


High-level functional expression of a fungal xylose isomerase: the key to efficient ethanolic fermentation of xylose by ?
journal, October 2003


Deletion of the GRE3 Aldose Reductase Gene and Its Influence on Xylose Metabolism in Recombinant Strains of Saccharomyces cerevisiae Expressing the xylA and XKS1 Genes
journal, December 2001