Isotopically labeled compositions and method

Title: Isotopically labeled compositions and method

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Abstract

Compounds having stable isotopes .sup.13C and/or .sup.2H were synthesized from precursor compositions having solid phase supports or affinity tags.

Inventors:

Schmidt, Jurgen G ^[1]; Kimball, David B ^[1]; Alvarez, Marc A ^[2]; Williams, Robert F ^[1]; Martinez, Rudolfo A ^[2]

Los Alamos, NM
Santa Fe, NM

Issue Date:: 2011-07-12

Research Org.:: Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 1019428

Patent Number(s):: 7977102

Application Number:: US Patent Application 11/818,984

Assignee:: Los Alamos National Security, LLC (Los Alamos, NM)

Patent Classifications (CPCs):: C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION

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C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C317/22 - with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
C07C317/44 - having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T436/13 - Tracers or tags

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C323/20 - with singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
C07C323/52 - the carbon skeleton being acyclic and saturated

Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
Y10T436/25375 - Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C391/02 - having selenium atoms bound to carbon atoms of six-membered aromatic rings

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07B - GENERAL METHODS OF ORGANIC CHEMISTRY
C07B2200/05 - Isotopically modified compounds, e.g. labelled

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C323/36 - the sulfur atom of the sulfide group being further bound to an acyclic carbon atom
C07C2602/10 - the other ring being six-membered, e.g. tetraline

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07B - GENERAL METHODS OF ORGANIC CHEMISTRY
C07B2200/11 - Compounds covalently bound to a solid support

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C2603/24 - Anthracenes
C07C323/60 - with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
C07C2602/08 - the other ring being five-membered, e.g. indane

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07B - GENERAL METHODS OF ORGANIC CHEMISTRY
C07B59/001 - {Acyclic or carbocyclic compounds}

C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
C07C323/32 - having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
C07C323/21 - with the sulfur atom of the thio group bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system

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DOE Contract Number:: AC52-06NA25396

Resource Type:: Patent

Country of Publication:: United States

Language:: English

Subject:: 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

Citation Formats


                    Schmidt, Jurgen G, Kimball, David B, Alvarez, Marc A, Williams, Robert F, and Martinez, Rudolfo A. Isotopically labeled compositions and method.  United States: N. p., 2011. 
        Web.

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                    Schmidt, Jurgen G, Kimball, David B, Alvarez, Marc A, Williams, Robert F, & Martinez, Rudolfo A. Isotopically labeled compositions and method.  United States.

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                    Schmidt, Jurgen G, Kimball, David B, Alvarez, Marc A, Williams, Robert F, and Martinez, Rudolfo A. Tue .  
        "Isotopically labeled compositions and method".  United States.  https://www.osti.gov/servlets/purl/1019428.

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@article{osti_1019428,

  title        = {Isotopically labeled compositions and method},

  author       = {Schmidt, Jurgen G and Kimball, David B and Alvarez, Marc A and Williams, Robert F and Martinez, Rudolfo A},

  abstractNote = {Compounds having stable isotopes .sup.13C and/or .sup.2H were synthesized from precursor compositions having solid phase supports or affinity tags.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2011},

  month        = {7}

}

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