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Title: Preconcentration and separation of analytes in microchannels

Abstract

Disclosed herein are methods and devices for preconcentrating and separating analytes such as proteins and polynucleotides in microchannels. As disclosed, at least one size-exclusion polymeric element is adjacent to processing area or an assay area in a microchannel which may be porous polymeric element. The size-exclusion polymeric element may be used to manipulate, e.g. concentrate, analytes in a sample prior to assaying in the assay area.

Inventors:
 [1];  [2];  [3];  [1]
  1. Tracy, CA
  2. Danville, CA
  3. Fremont, CA
Issue Date:
Research Org.:
Sandia Corporation (Livermore, CA)
Sponsoring Org.:
USDOE
OSTI Identifier:
1014940
Patent Number(s):
7828948
Application Number:
US Patent Application 11/536,753
Assignee:
Sandia Corporation (Livermore, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Hatch, Anson, Singh, Anup K, Herr, Amy E, and Throckmorton, Daniel J. Preconcentration and separation of analytes in microchannels. United States: N. p., 2010. Web.
Hatch, Anson, Singh, Anup K, Herr, Amy E, & Throckmorton, Daniel J. Preconcentration and separation of analytes in microchannels. United States.
Hatch, Anson, Singh, Anup K, Herr, Amy E, and Throckmorton, Daniel J. Tue . "Preconcentration and separation of analytes in microchannels". United States. https://www.osti.gov/servlets/purl/1014940.
@article{osti_1014940,
title = {Preconcentration and separation of analytes in microchannels},
author = {Hatch, Anson and Singh, Anup K and Herr, Amy E and Throckmorton, Daniel J},
abstractNote = {Disclosed herein are methods and devices for preconcentrating and separating analytes such as proteins and polynucleotides in microchannels. As disclosed, at least one size-exclusion polymeric element is adjacent to processing area or an assay area in a microchannel which may be porous polymeric element. The size-exclusion polymeric element may be used to manipulate, e.g. concentrate, analytes in a sample prior to assaying in the assay area.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2010},
month = {11}
}

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Works referenced in this record:

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