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Title: System and method for measuring particles in a sample stream of a flow cytometer or the like

Abstract

A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.

Inventors:
 [1];  [2]
  1. San Juan Pueblo, NM
  2. Santa Fe, NM
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1014882
Patent Number(s):
7835000
Application Number:
US Patent Application 11/593,312
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Country of Publication:
United States
Language:
English

Citation Formats

Graves, Steven W, and Habberset, Robert C. System and method for measuring particles in a sample stream of a flow cytometer or the like. United States: N. p., 2010. Web.
Graves, Steven W, & Habberset, Robert C. System and method for measuring particles in a sample stream of a flow cytometer or the like. United States.
Graves, Steven W, and Habberset, Robert C. Tue . "System and method for measuring particles in a sample stream of a flow cytometer or the like". United States. https://www.osti.gov/servlets/purl/1014882.
@article{osti_1014882,
title = {System and method for measuring particles in a sample stream of a flow cytometer or the like},
author = {Graves, Steven W and Habberset, Robert C},
abstractNote = {A system and method for analyzing a particle in a sample stream of a flow cytometer or the like. The system has a light source, such as a laser pointer module, for generating a low powered light beam and a fluidics apparatus which is configured to transport particles in the sample stream at substantially low velocity through the light beam for interrogation. Detectors, such as photomultiplier tubes, are configured to detect optical signals generated in response to the light beam impinging the particles. Signal conditioning circuitry is connected to each of the detectors to condition each detector output into electronic signals for processing and is designed to have a limited frequency response to filter high frequency noise from the detector output signals.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2010},
month = {11}
}

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