Methods and devices for high-throughput dielectrophoretic concentration
Abstract
Disclosed herein are methods and devices for assaying and concentrating analytes in a fluid sample using dielectrophoresis. As disclosed, the methods and devices utilize substrates having a plurality of pores through which analytes can be selectively prevented from passing, or inhibited, on application of an appropriate electric field waveform. The pores of the substrate produce nonuniform electric field having local extrema located near the pores. These nonuniform fields drive dielectrophoresis, which produces the inhibition. Arrangements of electrodes and porous substrates support continuous, bulk, multi-dimensional, and staged selective concentration.
- Inventors:
-
- San Francisco, CA
- Livermore, CA
- Germantown, MD
- Ann Arbor, MI
- Escalon, CA
- Issue Date:
- Research Org.:
- Sandia Corporation (Livermore, CA)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1014186
- Patent Number(s):
- 7666289
- Application Number:
- US Patent Application 12/202,489
- Assignee:
- Sandia Corporation (Livermore, CA)
- Patent Classifications (CPCs):
-
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10T - TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
B - PERFORMING OPERATIONS B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL B01D - SEPARATION
- DOE Contract Number:
- AC04-94AL85000
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Simmons, Blake A, Cummings, Eric B, Fiechtner, Gregory J, Fintschenko, Yolanda, McGraw, Gregory J, and Salmi, Allen. Methods and devices for high-throughput dielectrophoretic concentration. United States: N. p., 2010.
Web.
Simmons, Blake A, Cummings, Eric B, Fiechtner, Gregory J, Fintschenko, Yolanda, McGraw, Gregory J, & Salmi, Allen. Methods and devices for high-throughput dielectrophoretic concentration. United States.
Simmons, Blake A, Cummings, Eric B, Fiechtner, Gregory J, Fintschenko, Yolanda, McGraw, Gregory J, and Salmi, Allen. Tue .
"Methods and devices for high-throughput dielectrophoretic concentration". United States. https://www.osti.gov/servlets/purl/1014186.
@article{osti_1014186,
title = {Methods and devices for high-throughput dielectrophoretic concentration},
author = {Simmons, Blake A and Cummings, Eric B and Fiechtner, Gregory J and Fintschenko, Yolanda and McGraw, Gregory J and Salmi, Allen},
abstractNote = {Disclosed herein are methods and devices for assaying and concentrating analytes in a fluid sample using dielectrophoresis. As disclosed, the methods and devices utilize substrates having a plurality of pores through which analytes can be selectively prevented from passing, or inhibited, on application of an appropriate electric field waveform. The pores of the substrate produce nonuniform electric field having local extrema located near the pores. These nonuniform fields drive dielectrophoresis, which produces the inhibition. Arrangements of electrodes and porous substrates support continuous, bulk, multi-dimensional, and staged selective concentration.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2010},
month = {2}
}
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