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Title: Direct imaging of neural currents using ultra-low field magnetic resonance techniques

Using resonant interactions to directly and tomographically image neural activity in the human brain using magnetic resonance imaging (MRI) techniques at ultra-low field (ULF), the present inventors have established an approach that is sensitive to magnetic field distributions local to the spin population in cortex at the Larmor frequency of the measurement field. Because the Larmor frequency can be readily manipulated (through varying B.sub.m), one can also envision using ULF-DNI to image the frequency distribution of the local fields in cortex. Such information, taken together with simultaneous acquisition of MEG and ULF-NMR signals, enables non-invasive exploration of the correlation between local fields induced by neural activity in cortex and more `distant` measures of brain activity such as MEG and EEG.
Inventors:
 [1];  [1];  [1];  [1];  [2]
  1. Los Alamos, NM
  2. (Los Alamos, NM)
Issue Date:
OSTI Identifier:
1013688
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM) LANL
Patent Number(s):
7,573,268
Application Number:
11/678,023
Contract Number:
W-7405-ENG-36
Research Org:
Los Alamos National Security, LLC (Los Alamos, NM)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

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