Method of making gold thiolate and photochemically functionalized microcantilevers
Abstract
Highly sensitive sensor platforms for the detection of specific reagents, such as chromate, gasoline and biological species, using microcantilevers and other microelectromechanical systems (MEMS) whose surfaces have been modified with photochemically attached organic monolayers, such as self-assembled monolayers (SAM), or gold-thiol surface linkage are taught. The microcantilever sensors use photochemical hydrosilylation to modify silicon surfaces and gold-thiol chemistry to modify metallic surfaces thereby enabling individual microcantilevers in multicantilever array chips to be modified separately. Terminal vinyl substituted hydrocarbons with a variety of molecular recognition sites can be attached to the surface of silicon via the photochemical hydrosilylation process. By focusing the activating UV light sequentially on selected silicon or silicon nitride hydrogen terminated surfaces and soaking or spotting selected metallic surfaces with organic thiols, sulfides, or disulfides, the microcantilevers are functionalized. The device and photochemical method are intended to be integrated into systems for detecting specific agents including chromate groundwater contamination, gasoline, and biological species.
- Inventors:
-
- Knoxville, TN
- Nottingham, GB
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1013636
- Patent Number(s):
- 7579052
- Application Number:
- 11/859,047
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
B - PERFORMING OPERATIONS B82 - NANOTECHNOLOGY B82Y - SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- AC05-00OR22725
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Boiadjiev, Vassil I, Brown, Gilbert M, Pinnaduwage, Lal A, Thundat, Thomas G, Bonnesen, Peter V, and Goretzki, Gudrun. Method of making gold thiolate and photochemically functionalized microcantilevers. United States: N. p., 2009.
Web.
Boiadjiev, Vassil I, Brown, Gilbert M, Pinnaduwage, Lal A, Thundat, Thomas G, Bonnesen, Peter V, & Goretzki, Gudrun. Method of making gold thiolate and photochemically functionalized microcantilevers. United States.
Boiadjiev, Vassil I, Brown, Gilbert M, Pinnaduwage, Lal A, Thundat, Thomas G, Bonnesen, Peter V, and Goretzki, Gudrun. Tue .
"Method of making gold thiolate and photochemically functionalized microcantilevers". United States. https://www.osti.gov/servlets/purl/1013636.
@article{osti_1013636,
title = {Method of making gold thiolate and photochemically functionalized microcantilevers},
author = {Boiadjiev, Vassil I and Brown, Gilbert M and Pinnaduwage, Lal A and Thundat, Thomas G and Bonnesen, Peter V and Goretzki, Gudrun},
abstractNote = {Highly sensitive sensor platforms for the detection of specific reagents, such as chromate, gasoline and biological species, using microcantilevers and other microelectromechanical systems (MEMS) whose surfaces have been modified with photochemically attached organic monolayers, such as self-assembled monolayers (SAM), or gold-thiol surface linkage are taught. The microcantilever sensors use photochemical hydrosilylation to modify silicon surfaces and gold-thiol chemistry to modify metallic surfaces thereby enabling individual microcantilevers in multicantilever array chips to be modified separately. Terminal vinyl substituted hydrocarbons with a variety of molecular recognition sites can be attached to the surface of silicon via the photochemical hydrosilylation process. By focusing the activating UV light sequentially on selected silicon or silicon nitride hydrogen terminated surfaces and soaking or spotting selected metallic surfaces with organic thiols, sulfides, or disulfides, the microcantilevers are functionalized. The device and photochemical method are intended to be integrated into systems for detecting specific agents including chromate groundwater contamination, gasoline, and biological species.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2009},
month = {8}
}
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