67549 SNL true https://github.com/sandialabs/PRIME OS S 2021-02-03 PRIME https://doi.org/10.11578/dc.20211202.2 SAND2021-0565 O PRIME is a modeling framework designed for the real-time characterization and forecasting of partially observed epidemics. The method is designed to help guide medical resource allocation in the early epoch of the outbreak. Characterization is the estimation of infection spread parameters using daily counts of symptomatic patients. The estimation problem is posed as one of Bayesian inference and solved using a Markov Chain Monte Carlo technique. The framework can accommodate multiple epidemic waves and can help identify different disease dynamics at the regional, state, and country levels. Examples are provided using publicly available COVID-19 data. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s National Nuclear Security Administration under contract DE-NA0003525. 1 United States Sandia National Laboratories SCR #2595 2021-12-02 2021-12-02 false false Cosmin Safta Sandia National Lab. (SNL-CA), Livermore, CA (United States) Sandia National Lab. (SNL-NM), Albuquerque, NM (United States) Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States) Jaideep Ray Sandia National Lab. (SNL-CA), Livermore, CA (United States) Sandia National Lab. (SNL-NM), Albuquerque, NM (United States) Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States) Patrick Blonigan Sandia National Lab. (SNL-CA), Livermore, CA (United States) Sandia National Lab. (SNL-NM), Albuquerque, NM (United States) Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States) Kenny Chowdhary Sandia National Lab. (SNL-CA), Livermore, CA (United States) Sandia National Lab. (SNL-NM), Albuquerque, NM (United States) Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States) USDOE NA0003525 true Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States) true Python BSD 2-clause "Simplified" License