162810 SNL true https://github.com/sandialabs/PRIME-VI OS S 2024-08-04 Prime VI https://doi.org/10.11578/dc.20250905.9 SAND2025-03757O Prime VI is a distribution-of-disease outbreak model calibration code based on variational inference. It accompanies a publication for submission to Statistics in Medicine journal, and the code will be maintained for open-source use on Sandia's GitLab. The software provides methods for calibrating an epidemiological model to measured case-count data for a multitude of correlated spatial regions. The code solves a Bayesian inverse problem for model calibration where the posterior over-model parameters are approximated through a custom implementation of variational inference. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology & Engineering Solutions of Sandia, LLC, a wholly owned subsidiary of Honeywell International Inc., for the U.S. Department of Energy’s National Nuclear Security Administration under contract DE-NA0003525. 0.1 United States Sandia National Laboratories SCR #3072.0 2025-09-05 2025-09-05 false copyrightadmin@sandia.gov false Cosmin Safta Sandia National Lab. (SNL-CA), Livermore, CA (United States) Sandia National Lab. (SNL-NM), Albuquerque, NM (United States) Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States) Jaideep Ray Sandia National Lab. (SNL-CA), Livermore, CA (United States) Sandia National Lab. (SNL-NM), Albuquerque, NM (United States) Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States) Wyatt Bridgman Sandia National Lab. (SNL-CA), Livermore, CA (United States) Sandia National Lab. (SNL-NM), Albuquerque, NM (United States) Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States) USDOE NA0003525 true Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States) true Python 3.11.5 BSD 2-clause "Simplified" License