Abstract
Light sheet microscopy has made possible the 3D imaging of both fixed and live biological tissue, with samples as large as
the entire mouse brain. We fine-tuned an existing model, TrailMap, using expert labeled data from axonal structures in neocortex. Without
changing the network architecture, we implemented nnU-Net framework modifications in data augmentation, data
foreground sampling, window learning rate, and the inference overlap method. The resulting model from these combined
approaches yielded an improved F1 score
- Developers:
-
Oostrom, Marjolein [1] ; Bramer, Lisa [1]
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Release Date:
- 2023-10-04
- Project Type:
- Open Source, Publicly Available Repository
- Software Type:
- Scientific
- Licenses:
-
BSD 2-clause "Simplified" License
- Sponsoring Org.:
-
USDOEPrimary Award/Contract Number:AC05-76RL01830
- Code ID:
- 114417
- Site Accession Number:
- Battelle IPID 32777-E
- Research Org.:
- Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
- Country of Origin:
- United States
Citation Formats
Oostrom, Marjolein, and Bramer, Lisa.
pnnl/brain_ohsu.
Computer Software.
https://github.com/pnnl/brain_ohsu.
USDOE.
04 Oct. 2023.
Web.
doi:10.11578/dc.20231004.1.
Oostrom, Marjolein, & Bramer, Lisa.
(2023, October 04).
pnnl/brain_ohsu.
[Computer software].
https://github.com/pnnl/brain_ohsu.
https://doi.org/10.11578/dc.20231004.1.
Oostrom, Marjolein, and Bramer, Lisa.
"pnnl/brain_ohsu." Computer software.
October 04, 2023.
https://github.com/pnnl/brain_ohsu.
https://doi.org/10.11578/dc.20231004.1.
@misc{
doecode_114417,
title = {pnnl/brain_ohsu},
author = {Oostrom, Marjolein and Bramer, Lisa},
abstractNote = {Light sheet microscopy has made possible the 3D imaging of both fixed and live biological tissue, with samples as large as
the entire mouse brain. We fine-tuned an existing model, TrailMap, using expert labeled data from axonal structures in neocortex. Without
changing the network architecture, we implemented nnU-Net framework modifications in data augmentation, data
foreground sampling, window learning rate, and the inference overlap method. The resulting model from these combined
approaches yielded an improved F1 score},
doi = {10.11578/dc.20231004.1},
url = {https://doi.org/10.11578/dc.20231004.1},
howpublished = {[Computer Software] \url{https://doi.org/10.11578/dc.20231004.1}},
year = {2023},
month = {oct}
}