Omics-Lethal Human Viruses, West Nile Experiment WGCN002

Anderson, Lindsey N.; Eisfeld, Amie J.; Waters, Katrina M.

doi:10.25584/LHVWGCN002/1661957

Title: Omics-Lethal Human Viruses, West Nile Experiment WGCN002

Dataset
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Abstract

The purpose of this experiment was to evaluate the host response to wild-type West Nile virus infectious clone (WNV-NY99 clone 382) and mutant (WNVE218A) virus infection. Sample data was obtained from mouse granule cell neurons for mRNA and miRNA expression analysis. See Experiment WGCN003 for corresponding independent biological replicate study. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific West Nile virus infection.

Authors:

;

Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Pacific Northwest National Laboratory, Biological Sciences Division
Univ. of Wisconsin, Madison, WI (United States). School of Veterinary Medicine. Pathology Department
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Publication Date:: 2021-01-18

Other Number(s):: WGCN002
NCBI BioProject: PRJNA282548 (mRNA); NCBI BioProject: PRJNA282547 (miRNA); GEO Series: GSE68380 (mRNA); GEO Series: GSE68381 (miRNA)

DOE Contract Number:: AC05-76RL01830

Research Org.:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Sponsoring Org.:: USDOE Office of Science (SC); National Institute of Allergy and Infectious Diseases (NIAID)

Collaborations:: Modeling Host Responses to Understand Severe Human Virus Infections Program Project

Subject:: 59 BASIC BIOLOGICAL SCIENCES; BioProject Accession Number [NCIT:C175890]; Data Download [schema:DataDownload]; Gene expression profile data [edam.data:0928]; Immune Response [GO:0006955]; Mus musculus [NCBITAXON:10090]; Omics [edam.topic:3391]; Time Sampled Measurement Datasets [IAO:0000584]; Virology [edam.topic:0781]; West Nile Virus [NCBITAXON:11082]; data transformation [SIO:000594]; differential expression analysis [SWO:7000018]

OSTI Identifier:: 1661957

DOI:: https://doi.org/10.25584/LHVWGCN002/1661957

Citation Formats


                    Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. Omics-Lethal Human Viruses, West Nile Experiment WGCN002.  United States: N. p., 2021. 
        Web.  doi:10.25584/LHVWGCN002/1661957.

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                    Anderson, Lindsey N., Eisfeld, Amie J., & Waters, Katrina M. Omics-Lethal Human Viruses, West Nile Experiment WGCN002.  United States.  doi:https://doi.org/10.25584/LHVWGCN002/1661957

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                    Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. 2021.  
"Omics-Lethal Human Viruses, West Nile Experiment WGCN002".  United States.  doi:https://doi.org/10.25584/LHVWGCN002/1661957.  https://www.osti.gov/servlets/purl/1661957. Pub date:Mon Jan 18 04:00:00 UTC 2021

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@article{osti_1661957,

  title        = {Omics-Lethal Human Viruses, West Nile Experiment WGCN002},

  author       = {Anderson, Lindsey N. and Eisfeld, Amie J. and Waters, Katrina M.},

  abstractNote = {The purpose of this experiment was to evaluate the host response to wild-type West Nile virus infectious clone (WNV-NY99 clone 382) and mutant (WNVE218A) virus infection. Sample data was obtained from mouse granule cell neurons for mRNA and miRNA expression analysis. See Experiment WGCN003 for corresponding independent biological replicate study. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific West Nile virus infection.},

  doi          = {10.25584/LHVWGCN002/1661957},

  journal      = {},

  number       = ,

  volume       = ,

  place        = {United States},

  year         = {2021},

  month        = {1}

}

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DOI: https://doi.org/10.25584/LHVWGCN002/1661957

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