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Title: Omics-Lethal Human Viruses, West Nile Experiment WGCN002

Abstract

The purpose of this experiment was to evaluate the host response to wild-type West Nile virus infectious clone (WNV-NY99 clone 382) and mutant (WNVE218A) virus infection. Sample data was obtained from mouse granule cell neurons for mRNA and miRNA expression analysis. See Experiment WGCN003 for corresponding independent biological replicate study. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific West Nile virus infection.

Authors:
ORCiD logo ; ORCiD logo ; ORCiD logo
  1. Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
  2. Univ. of Wisconsin, Madison, WI (United States). School of Veterinary Medicine. Pathology Department
Publication Date:
Other Number(s):
WGCN002
NCBI BioProject: PRJNA282548 (mRNA);NCBI BioProject: PRJNA282547 (miRNA);GEO Series: GSE68380 (mRNA);GEO Series: GSE68381 (miRNA)
DOE Contract Number:  
AC05-76RL01830
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE Office of Science (SC); National Institute of Allergy and Infectious Diseases (NIAID)
Collaborations:
Modeling Host Responses to Understand Severe Human Virus Infections Program Project
Subject:
59 BASIC BIOLOGICAL SCIENCES
Keywords:
Virology [edam.topic:0781]; Immune Response [GO:0006955]; Mus musculus [NCBITAXON:10090]; West Nile Virus [NCBITAXON:11082]; Time Sampled Measurement Datasets [IAO:0000584]; Gene expression profile data [edam.data:0928]; BioProject Accession Number [NCIT:C175890]; Omics [edam.topic:3391]; data transformation [SIO:000594]; differential expression analysis [SWO:7000018]; Data Download [schema:DataDownload]
OSTI Identifier:
1661957
DOI:
https://doi.org/10.25584/LHVWGCN002/1661957

Citation Formats

Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. Omics-Lethal Human Viruses, West Nile Experiment WGCN002. United States: N. p., 2021. Web. doi:10.25584/LHVWGCN002/1661957.
Anderson, Lindsey N., Eisfeld, Amie J., & Waters, Katrina M. Omics-Lethal Human Viruses, West Nile Experiment WGCN002. United States. doi:https://doi.org/10.25584/LHVWGCN002/1661957
Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. 2021. "Omics-Lethal Human Viruses, West Nile Experiment WGCN002". United States. doi:https://doi.org/10.25584/LHVWGCN002/1661957. https://www.osti.gov/servlets/purl/1661957. Pub date:Mon Jan 18 00:00:00 EST 2021
@article{osti_1661957,
title = {Omics-Lethal Human Viruses, West Nile Experiment WGCN002},
author = {Anderson, Lindsey N. and Eisfeld, Amie J. and Waters, Katrina M.},
abstractNote = {The purpose of this experiment was to evaluate the host response to wild-type West Nile virus infectious clone (WNV-NY99 clone 382) and mutant (WNVE218A) virus infection. Sample data was obtained from mouse granule cell neurons for mRNA and miRNA expression analysis. See Experiment WGCN003 for corresponding independent biological replicate study. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific West Nile virus infection.},
doi = {10.25584/LHVWGCN002/1661957},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {1}
}

Works referenced in this record:

Wgcn003
dataset, January 2020


    Works referencing / citing this record:

    PNNL DataHub Omics Lethal Human Viruses Project, Modeling Host Responses to West Nile Infection Post-Processed Data Package DOIs
    dataset, January 2021