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Title: Omics-Lethal Human Viruses, West Nile Experiment WCN002

Abstract

The purpose of this experiment was to evaluate the host response to wild-type West Nile virus (WNV NY99 clone 382) and mutant (WNVE218A) virus infection. Sample data was obtained from mouse cortical neuron tissue and processed for mRNA and miRNA expression analysis. This data set comprises two complete biological replicate experiments conducted in the same conditions and with data processed independently (WCN003). Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific West Nile virus infection.

Authors:
ORCiD logo ; ORCiD logo ; ORCiD logo
  1. Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
  2. Univ. of Wisconsin, Madison, WI (United States). School of Veterinary Medicine. Pathology Department
Publication Date:
Other Number(s):
WCN002
NCBI BioProject: PRJNA280008 (mRNA);NCBI BioProject: PRJNA280010 (miRNA);GEO Series: GSE67473 (mRNA);GEO Series: GSE67474 (miRNA)
DOE Contract Number:  
AC05-76RL01830
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE Office of Science (SC); National Institute of Allergy and Infectious Diseases (NIAID)
Collaborations:
Modeling Host Responses to Understand Severe Human Virus Infections Program Project
Subject:
59 BASIC BIOLOGICAL SCIENCES
Keywords:
Virology [edam.topic:0781]; Immune Response [GO:0006955]; Mus musculus [NCBITAXON:10090]; West Nile Virus [NCBITAXON:11082]; Time Sampled Measurement Datasets [IAO:0000584]; Gene expression profile data [edam.data:0928]; BioProject Accession Number [NCIT:C175890]; Omics [edam.topic:3391]; data transformation [SIO:000594]; differential expression analysis [SWO:7000018]; Data Download [schema:DataDownload]
OSTI Identifier:
1661950
DOI:
https://doi.org/10.25584/LHVWCN002/1661950

Citation Formats

Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. Omics-Lethal Human Viruses, West Nile Experiment WCN002. United States: N. p., 2021. Web. doi:10.25584/LHVWCN002/1661950.
Anderson, Lindsey N., Eisfeld, Amie J., & Waters, Katrina M. Omics-Lethal Human Viruses, West Nile Experiment WCN002. United States. doi:https://doi.org/10.25584/LHVWCN002/1661950
Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. 2021. "Omics-Lethal Human Viruses, West Nile Experiment WCN002". United States. doi:https://doi.org/10.25584/LHVWCN002/1661950. https://www.osti.gov/servlets/purl/1661950. Pub date:Mon Jan 18 00:00:00 EST 2021
@article{osti_1661950,
title = {Omics-Lethal Human Viruses, West Nile Experiment WCN002},
author = {Anderson, Lindsey N. and Eisfeld, Amie J. and Waters, Katrina M.},
abstractNote = {The purpose of this experiment was to evaluate the host response to wild-type West Nile virus (WNV NY99 clone 382) and mutant (WNVE218A) virus infection. Sample data was obtained from mouse cortical neuron tissue and processed for mRNA and miRNA expression analysis. This data set comprises two complete biological replicate experiments conducted in the same conditions and with data processed independently (WCN003). Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset downloads have a direct relationship to a primary sample submission corresponding to a specific West Nile virus infection.},
doi = {10.25584/LHVWCN002/1661950},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2021},
month = {1}
}

Works referenced in this record:

Wcn003
dataset, January 2020


    Works referencing / citing this record:

    PNNL DataHub Omics Lethal Human Viruses Project, Modeling Host Responses to West Nile Infection Post-Processed Data Package DOIs
    dataset, January 2021