Omics-Lethal Human Viruses, Interferon-Stimulated Response Experiment IFNMVE001

Anderson, Lindsey N.; Eisfeld, Amie J.; Waters, Katrina M.

doi:10.25584/LHVIFNMVE001/1661928

Title: Omics-Lethal Human Viruses, Interferon-Stimulated Response Experiment IFNMVE001

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Abstract

The purpose of this experiment was to evaluate the human host interferon-stimulated cellular response to interferon alpha/beta (IFNα/β) or gamma (INFγ) treatment. Sample data was obtained from primary lung microvascular endothelial cells (MVE) treated with or without human IFNαβ or INFγ for mRNA transcriptome expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset download have a direct relationship to a primary sample submission corresponding to a specific interferon response to viral infection.

Authors:

;

Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Pacific Northwest National Laboratory, Biological Sciences Division
Univ. of Wisconsin, Madison, WI (United States). School of Veterinary Medicine. Pathology Department
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Publication Date:: 2021-01-18

Other Number(s):: IFNMVE001
NCBI BioProject: PRJNA417087 (mRNA); GEO Series: GSE106524 (mRNA)

DOE Contract Number:: AC05-76RL01830

Research Org.:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Sponsoring Org.:: USDOE Office of Science (SC); National Institute of Allergy and Infectious Diseases (NIAID)

Collaborations:: Modeling Host Responses to Understand Severe Human Virus Infections Program Project

Subject:: 59 BASIC BIOLOGICAL SCIENCES; BioProject Accession Number [NCIT:C175890]; Data Download [schema:DataDownload]; Gene expression profile data [edam.data:0928]; Human Interferon [NCIT:C20493]; Human virus [NCIT:C14317]; Immune Response [GO:0006955]; Interferon Alpha [NCIT:C20494]; Interferon Beta [NCIT:C20495]; Interferon Gamma [NCIT:C20496]; Omics [edam.topic:3391]; Time Sampled Measurement Datasets [IAO:0000584]; Virology [edam.topic:0781]; data transformation [SIO:000594]; differential expression analysis [SWO:7000018]

OSTI Identifier:: 1661928

DOI:: https://doi.org/10.25584/LHVIFNMVE001/1661928

Citation Formats


                    Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. Omics-Lethal Human Viruses, Interferon-Stimulated Response Experiment IFNMVE001.  United States: N. p., 2021. 
        Web.  doi:10.25584/LHVIFNMVE001/1661928.

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                    Anderson, Lindsey N., Eisfeld, Amie J., & Waters, Katrina M. Omics-Lethal Human Viruses, Interferon-Stimulated Response Experiment IFNMVE001.  United States.  doi:https://doi.org/10.25584/LHVIFNMVE001/1661928

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                    Anderson, Lindsey N., Eisfeld, Amie J., and Waters, Katrina M. 2021.  
"Omics-Lethal Human Viruses, Interferon-Stimulated Response Experiment IFNMVE001".  United States.  doi:https://doi.org/10.25584/LHVIFNMVE001/1661928.  https://www.osti.gov/servlets/purl/1661928. Pub date:Mon Jan 18 04:00:00 UTC 2021

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@article{osti_1661928,

  title        = {Omics-Lethal Human Viruses, Interferon-Stimulated Response Experiment IFNMVE001},

  author       = {Anderson, Lindsey N. and Eisfeld, Amie J. and Waters, Katrina M.},

  abstractNote = {The purpose of this experiment was to evaluate the human host interferon-stimulated cellular response to interferon alpha/beta (IFNα/β) or gamma (INFγ) treatment. Sample data was obtained from primary lung microvascular endothelial cells (MVE) treated with or without human IFNαβ or INFγ for mRNA transcriptome expression analysis. Secondary host-associated viral dataset downloads contain one or more statistically processed (normalization data transformation) quantitative dataset collections resulting in qualitative expression analyses of primary host-pathogen experimental study designs. Transcriptomics dataset download have a direct relationship to a primary sample submission corresponding to a specific interferon response to viral infection.},

  doi          = {10.25584/LHVIFNMVE001/1661928},

  journal      = {},

  number       = ,

  volume       = ,

  place        = {United States},

  year         = {2021},

  month        = {1}

}

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DOI: https://doi.org/10.25584/LHVIFNMVE001/1661928

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