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Title: Using the Antenna Effect as a Spectroscopic Tool; Photophysics and Solution Thermodynamics of the Model Luminescent Hydroxypyridonate Complex [EuIII(3,4,3-LI(1,2-HOPO))]-

Abstract

While widely used in bioassays, the spectrofluorimetric method described here uses the antenna effect as a tool to probe the thermodynamic parameters of ligands that sensitize lanthanide luminescence. The Eu3+ coordination chemistry, solution thermodynamic stability and photophysical properties of the spermine-based hydroxypyridonate octadentate chelator 3,4,3-LI(1,2-HOPO) are reported. The complex [EuIII(3,4,3-LI(1,2-HOPO))]- luminesces with a long lifetime (805 mu s) and a quantum yield of 7.0percent in aqueous solution, at pH 7.4. These remarkable optical properties were exploited to determine the high (and proton-independent) stability of the complex (log beta 110 = 20.2(2)) and to define the influence of the ligand scaffold on the stability and photophysical properties.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
Chemical Sciences Division
OSTI Identifier:
993490
Report Number(s):
LBNL-3011E
Journal ID: 1520-510X; TRN: US201023%%493
DOE Contract Number:  
DE-AC02-05CH11231; NIH AI074065-01
Resource Type:
Journal Article
Journal Name:
Inorganic Chemistry
Additional Journal Information:
Journal Volume: 48; Journal Issue: 23
Country of Publication:
United States
Language:
English
Subject:
37; ANTENNAS; AQUEOUS SOLUTIONS; CHEMISTRY; LIFETIME; LUMINESCENCE; OPTICAL PROPERTIES; PROBES; RARE EARTHS; STABILITY; THERMODYNAMICS

Citation Formats

Abergel, Rebecca J, D'Aleo, Anthony, Ng Pak Leung, Clara, Shuh, David, and Raymond, Kenneth. Using the Antenna Effect as a Spectroscopic Tool; Photophysics and Solution Thermodynamics of the Model Luminescent Hydroxypyridonate Complex [EuIII(3,4,3-LI(1,2-HOPO))]-. United States: N. p., 2009. Web. doi:10.1021/ic9013703.
Abergel, Rebecca J, D'Aleo, Anthony, Ng Pak Leung, Clara, Shuh, David, & Raymond, Kenneth. Using the Antenna Effect as a Spectroscopic Tool; Photophysics and Solution Thermodynamics of the Model Luminescent Hydroxypyridonate Complex [EuIII(3,4,3-LI(1,2-HOPO))]-. United States. doi:10.1021/ic9013703.
Abergel, Rebecca J, D'Aleo, Anthony, Ng Pak Leung, Clara, Shuh, David, and Raymond, Kenneth. Fri . "Using the Antenna Effect as a Spectroscopic Tool; Photophysics and Solution Thermodynamics of the Model Luminescent Hydroxypyridonate Complex [EuIII(3,4,3-LI(1,2-HOPO))]-". United States. doi:10.1021/ic9013703. https://www.osti.gov/servlets/purl/993490.
@article{osti_993490,
title = {Using the Antenna Effect as a Spectroscopic Tool; Photophysics and Solution Thermodynamics of the Model Luminescent Hydroxypyridonate Complex [EuIII(3,4,3-LI(1,2-HOPO))]-},
author = {Abergel, Rebecca J and D'Aleo, Anthony and Ng Pak Leung, Clara and Shuh, David and Raymond, Kenneth},
abstractNote = {While widely used in bioassays, the spectrofluorimetric method described here uses the antenna effect as a tool to probe the thermodynamic parameters of ligands that sensitize lanthanide luminescence. The Eu3+ coordination chemistry, solution thermodynamic stability and photophysical properties of the spermine-based hydroxypyridonate octadentate chelator 3,4,3-LI(1,2-HOPO) are reported. The complex [EuIII(3,4,3-LI(1,2-HOPO))]- luminesces with a long lifetime (805 mu s) and a quantum yield of 7.0percent in aqueous solution, at pH 7.4. These remarkable optical properties were exploited to determine the high (and proton-independent) stability of the complex (log beta 110 = 20.2(2)) and to define the influence of the ligand scaffold on the stability and photophysical properties.},
doi = {10.1021/ic9013703},
journal = {Inorganic Chemistry},
number = 23,
volume = 48,
place = {United States},
year = {2009},
month = {11}
}