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Title: Oxygen-resistant hydrogenases and methods for designing and making same

Patent ·
OSTI ID:986476

The invention provides oxygen- resistant iron-hydrogenases ([Fe]-hydrogenases) for use in the production of H2. Methods used in the design and engineering of the oxygen-resistant [Fe]-hydrogenases are disclosed, as are the methods of transforming and culturing appropriate host cells with the oxygen-resistant [Fe]-hydrogenases. Finally, the invention provides methods for utilizing the transformed, oxygen insensitive, host cells in the bulk production of H.sub.2 in a light catalyzed reaction having water as the reactant.

Research Organization:
Midwest Research Institute, Kansas City, MO (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC36-99GO10337
Assignee:
Allaince for Sustainable Energy, LLC (Golden, CO)
Patent Number(s):
7,501,270
Application Number:
10/553,097
OSTI ID:
986476
Country of Publication:
United States
Language:
English