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Title: Dielectrophoretic columnar focusing device

Abstract

A dielectrophoretic columnar focusing device uses interdigitated microelectrodes to provide a spatially non-uniform electric field in a fluid that generates a dipole within particles in the fluid. The electric field causes the particles to either be attracted to or repelled from regions where the electric field gradient is large, depending on whether the particles are more or less polarizable than the fluid. The particles can thereby be forced into well defined stable paths along the interdigitated microelectrodes. The device can be used for flow cytometry, particle control, and other process applications, including cell counting or other types of particle counting, and for separations in material control.

Inventors:
 [1];  [1];  [2]
  1. Albuquerque, NM
  2. Tijeras, NM
Publication Date:
Research Org.:
Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
985227
Patent Number(s):
7,713,395
Application Number:
11/401,714
Assignee:
Sandia Corporation (Albuquerque, NM)
DOE Contract Number:  
AC04-94AL85000
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
47 OTHER INSTRUMENTATION

Citation Formats

James, Conrad D, Galambos, Paul C, and Derzon, Mark S. Dielectrophoretic columnar focusing device. United States: N. p., 2010. Web.
James, Conrad D, Galambos, Paul C, & Derzon, Mark S. Dielectrophoretic columnar focusing device. United States.
James, Conrad D, Galambos, Paul C, and Derzon, Mark S. 2010. "Dielectrophoretic columnar focusing device". United States. https://www.osti.gov/servlets/purl/985227.
@article{osti_985227,
title = {Dielectrophoretic columnar focusing device},
author = {James, Conrad D and Galambos, Paul C and Derzon, Mark S},
abstractNote = {A dielectrophoretic columnar focusing device uses interdigitated microelectrodes to provide a spatially non-uniform electric field in a fluid that generates a dipole within particles in the fluid. The electric field causes the particles to either be attracted to or repelled from regions where the electric field gradient is large, depending on whether the particles are more or less polarizable than the fluid. The particles can thereby be forced into well defined stable paths along the interdigitated microelectrodes. The device can be used for flow cytometry, particle control, and other process applications, including cell counting or other types of particle counting, and for separations in material control.},
doi = {},
url = {https://www.osti.gov/biblio/985227}, journal = {},
number = ,
volume = ,
place = {United States},
year = {2010},
month = {5}
}

Works referenced in this record:

Surface Micromachined Dielectrophoretic Gates for the Front-End Device of a Biodetection System
journal, January 2006


Development of surface micromachining technologies for microfluidics and bioMEMS
conference, September 2001


Frequency and Voltage Dependence of the Dielectrophoretic Trapping of Short Lengths of DNA and dCTP in a Nanopipette
journal, February 2004


Combined field-induced dielectrophoresis and phase separation for manipulating particles in microfluidics
journal, December 2003


Molecular dielectrophoresis of biopolymers
journal, January 1994


Electronic manipulation of DNA, proteins, and nanoparticles for potential circuit assembly
journal, October 2004


Electrodeless Dielectrophoresis of Single- and Double-Stranded DNA
journal, October 2002