Red-shifted fluorescent proteins mPlum and mRaspberry and polynucleotides encoding the same

Tsien, Roger Y; Wang, Lei

Red-shifted fluorescent proteins mPlum and mRaspberry and polynucleotides encoding the same

Patent · 01 July 2008

OSTI ID:984485

Tsien, Roger Y ^[1]; Wang, Lei ^[2]

La Jolla, CA
San Diego, CA

Methods using somatic hypermutation (SHM) for producing polypeptide and nucleic acid variants, and nucleic acids encoding such polypeptide variants are disclosed. Such variants may have desired properties. Also disclosed are novel polypeptides, such as improved fluorescent proteins, produced by the novel methods, and nucleic acids, vectors, and host cells comprising such vectors.

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Research Organization:: University of California

Sponsoring Organization:: USDOE

DOE Contract Number:: FG03-01ER63276

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 7,393,923

Application Number:: 10/984,694

OSTI ID:: 984485

Country of Publication:: United States

Language:: English

References (23)

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