In Vitro Efficacy and Mechanistic Role of Indocyanine Green as a Photodynamic Therapy Agent for Human Melanoma
Journal Article
·
· Photodiagnosis and Photodynamic Therapy
Photodynamic therapy (PDT) is a promising treatment for superficial cancer. However, poor therapeutic results have been reported for melanoma, due to the high melanin content. Indocyanine green (ICG) has near infrared absorption (700-800nm) and melanins do not absorb strongly in this area. This study explores the efficiency of ICG as a PDT agent for human melanoma, and its mechanistic role in the cell death pathway.
- Research Organization:
- Brookhaven National Lab. (BNL), Upton, NY (United States). National Synchrotron Light Source
- Sponsoring Organization:
- Doe - Office Of Science
- DOE Contract Number:
- DE-AC02-98CH10886
- OSTI ID:
- 980263
- Report Number(s):
- BNL-93181-2010-JA; TRN: US201015%%1648
- Journal Information:
- Photodiagnosis and Photodynamic Therapy, Vol. 6, Issue 2
- Country of Publication:
- United States
- Language:
- English
Similar Records
In vitro efficiency and mechanistic role of indocyanine green as photodynamic therapy agent for human melanoma
Near-infrared-emitting heteroleptic cationic iridium complexes derived from 2,3-diphenylbenzo[g]quinoxaline as in vitro theranostic photodynamic therapy agents
Enhanced photodynamic efficacy towards melanoma cells by encapsulation of Pc4 in silica nanoparticles
Journal Article
·
Sat May 02 00:00:00 EDT 2009
· Photodiagnosis and Photodynamic Therapy
·
OSTI ID:980263
+4 more
Near-infrared-emitting heteroleptic cationic iridium complexes derived from 2,3-diphenylbenzo[g]quinoxaline as in vitro theranostic photodynamic therapy agents
Journal Article
·
Fri May 19 00:00:00 EDT 2017
· Dalton Transactions
·
OSTI ID:980263
+9 more
Enhanced photodynamic efficacy towards melanoma cells by encapsulation of Pc4 in silica nanoparticles
Journal Article
·
Tue Dec 01 00:00:00 EST 2009
· Toxicology and Applied Pharmacology
·
OSTI ID:980263
+2 more