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Title: Non-Targeted Effects of Ionizing Radiation: Implications for Risk Assessment and the Radiation Dose Response Profile

Journal Article · · Health Physics, 97(5):426-432

Radiation risks at low doses remain a hotly debated topic. Recent experimental advances in our understanding of effects occurring in the progeny of irradiated cells, and/or the non-irradiated neighbors of irradiated cells, i.e., non-targeted effects associated with exposure to ionizing radiation, have influenced this debate. The goal of this document is to summarize the current status of this debate and speculate on the potential impact of non-targeted effects on radiation risk assessment and the radiation dose response profile.

Research Organization:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC05-76RL01830
OSTI ID:
972961
Report Number(s):
PNNL-SA-63766; HLTPAO; KP1602020; TRN: US1001523
Journal Information:
Health Physics, 97(5):426-432, Vol. 97, Issue 5; ISSN 0017-9078
Country of Publication:
United States
Language:
English

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