2nd International Joint Topical Meeting on Emergency Preparedness and Response and Robotic and Remote Systems

Conference · Tue Jan 01 00:00:00 EST 2008

OSTI ID:969005

Lu, Po-Yung ^[1]; Thomas, Richard D. ^[2]; Wassom, John S. ^[3]

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1. ORNL
2. Intercet, Ltd.
3. Oak Ridge National Laboratory (Retired)

It is desirable for the Department of Energy/National Nuclear Security Administration emergency preparedness and response community to have available every resource to enhance its capabilities for assessing the health effects of environmental agents. Such resources will aid DOE/NNSA in achieving its goal of protecting the health and safety of workers, the public, and environment in event of the release of radiological, chemical, or biological agents into the environment. Studies are reported in this paper where composite data analyses were done for the chemicals included in DOE's Protective Action Criteria (PACs) database. PACs define the concentration of airborne chemicals at which protective actions are required. They are used by DOE/NNSA in developing Emergency Preparedness Procedures and for Operational Emergencies. Data analyses were conducted to discern structure-activity relationship patterns among PAC chemicals by assigned classification schemes based on the 30 accepted categories used by the EPA Gene-Tox Program. PAC chemicals were scored according to their frequency of distribution, severity of toxicity index, and structural classification. These studies yielded results that could be helpful in assessing the toxicity of new chemicals. It is suggested that provisions be made to include chemical structural information in the PAC database.

• Research Organization: Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
• Sponsoring Organization: USDOE National Nuclear Security Administration (NNSA)
• DOE Contract Number: DE-AC05-00OR22725
• OSTI ID: 969005
• Resource Relation: Conference: Emergency Management & Robotics for Hazardous Environments, Albuquerque, NM, USA, 20080309, 20080312
• Country of Publication: United States
• Language: English

Related Subjects

45 MILITARY TECHNOLOGY, WEAPONRY, AND NATIONAL DEFENSE
99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE
EMERGENCY PLANS
CHEMICAL WARFARE AGENTS
STRUCTURE-ACTIVITY RELATIONSHIPS
PUBLIC HEALTH
TOXICITY
INFORMATION SYSTEMS
Emergency management
toxic substances
chemical classification schemes