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Title: An ELISA Microarray Platform for Validating Cancer Biomarkers.

Abstract

The number of known circulating proteins that have potential for detecting cancer is rapidly growing. It seems clear, though, that variability in biomarker levels in both healthy and diseased populations will prevent most of these proteins from being useful. It also appears that a unique profile of biomarkers will be needed to accurately detect each type of cancer and that it will be necessary to evaluate blood samples from thousands of people to validate that profile. We are developing an antibody microarray platform that can be used to efficiently accomplish this task.

Authors:
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
948416
Report Number(s):
PNNL-SA-50987
400412000; TRN: US200906%%335
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Journal Article
Resource Relation:
Journal Name: BIOforum Europe, 10:14-15; Journal Volume: 10
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; BLOOD; ENZYME IMMUNOASSAY; NEOPLASMS; PROTEINS

Citation Formats

Zangar, Richard C. An ELISA Microarray Platform for Validating Cancer Biomarkers.. United States: N. p., 2006. Web.
Zangar, Richard C. An ELISA Microarray Platform for Validating Cancer Biomarkers.. United States.
Zangar, Richard C. Sun . "An ELISA Microarray Platform for Validating Cancer Biomarkers.". United States. doi:.
@article{osti_948416,
title = {An ELISA Microarray Platform for Validating Cancer Biomarkers.},
author = {Zangar, Richard C.},
abstractNote = {The number of known circulating proteins that have potential for detecting cancer is rapidly growing. It seems clear, though, that variability in biomarker levels in both healthy and diseased populations will prevent most of these proteins from being useful. It also appears that a unique profile of biomarkers will be needed to accurately detect each type of cancer and that it will be necessary to evaluate blood samples from thousands of people to validate that profile. We are developing an antibody microarray platform that can be used to efficiently accomplish this task.},
doi = {},
journal = {BIOforum Europe, 10:14-15},
number = ,
volume = 10,
place = {United States},
year = {Sun Dec 31 00:00:00 EST 2006},
month = {Sun Dec 31 00:00:00 EST 2006}
}