Experimental and Theoretical Measurements of Concentration Distributions in Acoustic Focusing Devices

Title: Experimental and Theoretical Measurements of Concentration Distributions in Acoustic Focusing Devices

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Abstract

We describe a modeling approach to capture the particle motion within an acoustic focusing microfluidic device. Our approach combines finite element models for the acoustic forces with analytical models for the fluid motion and uses these force fields to calculate the particle motion in a Brownian dynamics simulation. We compare results for the model with experimental measurements of the focusing efficiency within a microfabricated device. The results show good qualitative agreement over a range of acoustic driving voltages and particle sizes.

Authors:: Rose, K A; Fisher, K; Jung, B; Ness, K; Mariella, Jr, R P

Publication Date:: 2008-06-16

Research Org.:: Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

Sponsoring Org.:: USDOE

OSTI Identifier:: 945542

Report Number(s):: LLNL-CONF-404844
TRN: US200903%%633

DOE Contract Number:: W-7405-ENG-48

Resource Type:: Conference

Resource Relation:: Conference: Presented at: Micro Total Analysis Systems, San Diego, CA, United States, Oct 12 - Oct 16, 2008

Country of Publication:: United States

Language:: English

Subject:: 47 OTHER INSTRUMENTATION; ACOUSTICS; EFFICIENCY; FOCUSING; PARTICLE SIZE; SIMULATION

Citation Formats


                    Rose, K A, Fisher, K, Jung, B, Ness, K, and Mariella, Jr, R P. Experimental and Theoretical Measurements of Concentration Distributions in Acoustic Focusing Devices.  United States: N. p., 2008. 
        Web.

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                    Rose, K A, Fisher, K, Jung, B, Ness, K, & Mariella, Jr, R P. Experimental and Theoretical Measurements of Concentration Distributions in Acoustic Focusing Devices.  United States.

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                    Rose, K A, Fisher, K, Jung, B, Ness, K, and Mariella, Jr, R P. Mon .  
        "Experimental and Theoretical Measurements of Concentration Distributions in Acoustic Focusing Devices".  United States.  https://www.osti.gov/servlets/purl/945542.

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@article{osti_945542,

  title        = {Experimental and Theoretical Measurements of Concentration Distributions in Acoustic Focusing Devices},

  author       = {Rose, K A and Fisher, K and Jung, B and Ness, K and Mariella, Jr, R P},

  abstractNote = {We describe a modeling approach to capture the particle motion within an acoustic focusing microfluidic device. Our approach combines finite element models for the acoustic forces with analytical models for the fluid motion and uses these force fields to calculate the particle motion in a Brownian dynamics simulation. We compare results for the model with experimental measurements of the focusing efficiency within a microfabricated device. The results show good qualitative agreement over a range of acoustic driving voltages and particle sizes.},

  doi          = {},

  url          = {https://www.osti.gov/biblio/945542},
  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {2008},

  month        = {6}

}

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