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Title: Apparatus and method for monitoring breath acetone and diabetic diagnostics

Patent ·
OSTI ID:943439

An apparatus and method for monitoring diabetes through breath acetone detection and quantitation employs a microplasma source in combination with a spectrometer. The microplasma source provides sufficient energy to produce excited acetone fragments from the breath gas that emit light. The emitted light is sent to the spectrometer, which generates an emission spectrum that is used to detect and quantify acetone in the breath gas.

Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
W-7405-ENG-36
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM)
Patent Number(s):
7,417,730
Application Number:
11/395,733
OSTI ID:
943439
Country of Publication:
United States
Language:
English

References (11)

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Breath-Acetone and Blood-Sugar Measurements in Diabetes journal June 1969
Acetone in Alveolar air, and the Control of Diabetes journal November 1966
Simple, sensitive nitrogen analyzer based on pulsed miniplasma source emission spectrometry journal December 2003
Gas recognition using a neural network approach to plasma optical emission spectroscopy conference October 2000
Experimental study of breakdown voltage and effective secondary electron emission coefficient for a micro-plasma device journal February 2004
Measurements of Cavity Ringdown Spectroscopy of Acetone in the Ultraviolet and Near-Infrared Spectral Regions: Potential for Development of a Breath Analyzer journal July 2004
Trace gases in breath of healthy volunteers when fasting and after a protein-calorie meal: a preliminary study journal November 1999
A Low-Power, Atmospheric Pressure, Pulsed Plasma Source for Molecular Emission Spectrometry journal January 2001
GC Analysis of Human Breath with A Series-Coupled Column Ensemble and A Multibed Sorption Trap journal May 2003
Capillary-discharge-based portable detector for chemical vapor monitoring journal May 2003