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Title: Protein Microarrays--Without a Trace

Abstract

Many experimental approaches in biology and biophysics, as well as applications in diagnosis and drug discovery, require proteins to be immobilized on solid supports. Protein microarrays, for example, provide a high-throughput format to study biomolecular interactions. The technique employed for protein immobilization is a key to the success of these applications. Recent biochemical developments are allowing, for the first time, the selective and traceless immobilization of proteins generated by cell-free systems without the need for purification and/or reconcentration prior to the immobilization step.

Authors:
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
940883
Report Number(s):
UCRL-JRNL-230183
TRN: US200824%%379
DOE Contract Number:
W-7405-ENG-48
Resource Type:
Journal Article
Resource Relation:
Journal Name: BIOforum Europe, vol. 5, no. 1, June 1, 2007, pp. 30-33; Journal Volume: 5; Journal Issue: 1
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; BIOLOGY; BIOPHYSICS; DIAGNOSIS; PROTEINS; PURIFICATION

Citation Formats

Camarero, J A. Protein Microarrays--Without a Trace. United States: N. p., 2007. Web.
Camarero, J A. Protein Microarrays--Without a Trace. United States.
Camarero, J A. Thu . "Protein Microarrays--Without a Trace". United States. doi:. https://www.osti.gov/servlets/purl/940883.
@article{osti_940883,
title = {Protein Microarrays--Without a Trace},
author = {Camarero, J A},
abstractNote = {Many experimental approaches in biology and biophysics, as well as applications in diagnosis and drug discovery, require proteins to be immobilized on solid supports. Protein microarrays, for example, provide a high-throughput format to study biomolecular interactions. The technique employed for protein immobilization is a key to the success of these applications. Recent biochemical developments are allowing, for the first time, the selective and traceless immobilization of proteins generated by cell-free systems without the need for purification and/or reconcentration prior to the immobilization step.},
doi = {},
journal = {BIOforum Europe, vol. 5, no. 1, June 1, 2007, pp. 30-33},
number = 1,
volume = 5,
place = {United States},
year = {Thu Apr 05 00:00:00 EDT 2007},
month = {Thu Apr 05 00:00:00 EDT 2007}
}