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Ultrasonic analyte concentration and application in flow cytometry

Patent ·
OSTI ID:936222
 [1];  [1];  [2];  [1];  [1];  [1];  [3]
  1. Los Alamos, NM
  2. White Rock, NM
  3. San Juan Pueblo, NM
+ Show Author Affiliations
The present invention includes an apparatus and corresponding method for concentrating analytes within a fluid flowing through a tube using acoustic radiation pressure. The apparatus includes a function generator that outputs a radio frequency electrical signal to a transducer that transforms the radio frequency electric signal to an acoustic signal and couples the acoustic signal to the tube. The acoustic signal is converted within the tube to acoustic pressure that concentrates the analytes within the fluid.
Research Organization:
Los Alamos National Laboratory (LANL), Los Alamos, NM
Sponsoring Organization:
United States Department of Energy
DOE Contract Number:
W-7405-ENG-36
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM)
Patent Number(s):
7,340,957
Application Number:
10/979,065
OSTI ID:
936222
Country of Publication:
United States
Language:
English

References (3)

A numerically stable global matrix method for cylindrically layered shells excited by ring forces journal June 1994
Migration of suspended particles in plane stationary ultrasonic field journal January 1981
On the Acoustic Radiation Pressure on Spheres journal November 1934

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