skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM)

Abstract

The UCLA-DOE Institute of Genomics and Proteomics is an organized research unit of the University of California, sponsored by the Department of Energy through the mechanism of a Cooperative Agreement. Today the Institute consists of 10 Principal Investigators and 7 Associate Members, developing and applying technologies to promote the biological and environmental missions of the Department of Energy, and 5 Core Technology Centers to sustain this work. The focus is on understanding genomes, pathways and molecular machines in organisms of interest to DOE, with special emphasis on developing enabling technologies. Since it was founded in 1947, the UCLA-DOE Institute has adapted its mission to the research needs of DOE and its progenitor agencies as these research needs have changed. The Institute started as the AEC Laboratory of Nuclear Medicine, directed by Stafford Warren, who later became the founding Dean of the UCLA School of Medicine. In this sense, the entire UCLA medical center grew out of the precursor of our Institute. In 1963, the mission of the Institute was expanded into environmental studies by Director Ray Lunt. I became the third director in 1993, and in close consultation with David Galas and John Wooley of DOE, shifted the mission ofmore » the Institute towards genomics and proteomics. Since 1993, the Principal Investigators and Core Technology Centers are entirely new, and the Institute has separated from its former division concerned with PET imaging. The UCLA-DOE Institute shares the space of Boyer Hall with the Molecular Biology Institute, and assumes responsibility for the operation of the main core facilities. Fig. 1 gives the organizational chart of the Institute. Some of the benefits to the public of research carried out at the UCLA-DOE Institute include the following: The development of publicly accessible, web-based databases, including the Database of Protein Interactions, and the ProLinks database of genomicly inferred protein function linkages. The development of publicly accessible, web-based servers, including the HOTPATCH server, the ProKnow Server and the SAVEs server. All of these are accessible from the home page of the Institute. Advancing the science of bioenergy, in the laboratories of the Principal Investigators of the Institute, including the laboratories of Shimon Weiss, James Liao, James Bowie, Todd Yeates, Rob Gunsalus.« less

Authors:
Publication Date:
Research Org.:
The Regents of the University of California, Los Angeles
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
934813
Report Number(s):
DOE 87ER60615
TRN: US0806213
DOE Contract Number:  
FC03-87ER60615
Resource Type:
Technical Report
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY; BIOLOGY; EDUCATIONAL FACILITIES; MEDICAL ESTABLISHMENTS; MEDICINE; MOLECULAR BIOLOGY; NUCLEAR MEDICINE; PRECURSOR; PROTEINS; RESEARCH PROGRAMS; UCLA

Citation Formats

Eisenberg, David S. STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM). United States: N. p., 2008. Web. doi:10.2172/934813.
Eisenberg, David S. STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM). United States. doi:10.2172/934813.
Eisenberg, David S. Tue . "STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM)". United States. doi:10.2172/934813. https://www.osti.gov/servlets/purl/934813.
@article{osti_934813,
title = {STRUCTURAL BIOLOGY AND MOLECULAR MEDICINE RESEARCH PROGRAM (LSBMM)},
author = {Eisenberg, David S.},
abstractNote = {The UCLA-DOE Institute of Genomics and Proteomics is an organized research unit of the University of California, sponsored by the Department of Energy through the mechanism of a Cooperative Agreement. Today the Institute consists of 10 Principal Investigators and 7 Associate Members, developing and applying technologies to promote the biological and environmental missions of the Department of Energy, and 5 Core Technology Centers to sustain this work. The focus is on understanding genomes, pathways and molecular machines in organisms of interest to DOE, with special emphasis on developing enabling technologies. Since it was founded in 1947, the UCLA-DOE Institute has adapted its mission to the research needs of DOE and its progenitor agencies as these research needs have changed. The Institute started as the AEC Laboratory of Nuclear Medicine, directed by Stafford Warren, who later became the founding Dean of the UCLA School of Medicine. In this sense, the entire UCLA medical center grew out of the precursor of our Institute. In 1963, the mission of the Institute was expanded into environmental studies by Director Ray Lunt. I became the third director in 1993, and in close consultation with David Galas and John Wooley of DOE, shifted the mission of the Institute towards genomics and proteomics. Since 1993, the Principal Investigators and Core Technology Centers are entirely new, and the Institute has separated from its former division concerned with PET imaging. The UCLA-DOE Institute shares the space of Boyer Hall with the Molecular Biology Institute, and assumes responsibility for the operation of the main core facilities. Fig. 1 gives the organizational chart of the Institute. Some of the benefits to the public of research carried out at the UCLA-DOE Institute include the following: The development of publicly accessible, web-based databases, including the Database of Protein Interactions, and the ProLinks database of genomicly inferred protein function linkages. The development of publicly accessible, web-based servers, including the HOTPATCH server, the ProKnow Server and the SAVEs server. All of these are accessible from the home page of the Institute. Advancing the science of bioenergy, in the laboratories of the Principal Investigators of the Institute, including the laboratories of Shimon Weiss, James Liao, James Bowie, Todd Yeates, Rob Gunsalus.},
doi = {10.2172/934813},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2008},
month = {7}
}