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Title: Toward Electronic Conductance Characterization of DNA Nucleotide Bases

Abstract

We calculate electron-transport properties within equilibrium, linear transport theory through the DNA nucleotide bases spanning two gold nanowires. Our quantum mechanical calculations show that single configurations of DNA bases A, C, T, and G have significantly different charge conductance characteristics. This result is consistent with the notion that it is possible to read the nucleotide base sequence on an individual DNA heteropolymer which is moving through a gap between electrically biased nanoelectrodes by measuring the changes in the electron-transport conductance.

Authors:
 [1];  [1];  [1];  [1];  [2]
  1. ORNL
  2. University of Missouri, Columbia
Publication Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
Work for Others (WFO)
OSTI Identifier:
931920
DOE Contract Number:  
DE-AC05-00OR22725
Resource Type:
Conference
Resource Relation:
Conference: ChinaNano 2005 (China International Conference on Nanoscience and Technology), Beijing, China, 20050609, 20050611
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; DNA; GOLD; NUCLEOTIDES; TRANSPORT THEORY

Citation Formats

Lee, James Weifu, Krstic, Predrag S, Wells, Jack C, Fuentes-Cabrera, Miguel A, and Xu, Dong. Toward Electronic Conductance Characterization of DNA Nucleotide Bases. United States: N. p., 2007. Web.
Lee, James Weifu, Krstic, Predrag S, Wells, Jack C, Fuentes-Cabrera, Miguel A, & Xu, Dong. Toward Electronic Conductance Characterization of DNA Nucleotide Bases. United States.
Lee, James Weifu, Krstic, Predrag S, Wells, Jack C, Fuentes-Cabrera, Miguel A, and Xu, Dong. Mon . "Toward Electronic Conductance Characterization of DNA Nucleotide Bases". United States. doi:.
@article{osti_931920,
title = {Toward Electronic Conductance Characterization of DNA Nucleotide Bases},
author = {Lee, James Weifu and Krstic, Predrag S and Wells, Jack C and Fuentes-Cabrera, Miguel A and Xu, Dong},
abstractNote = {We calculate electron-transport properties within equilibrium, linear transport theory through the DNA nucleotide bases spanning two gold nanowires. Our quantum mechanical calculations show that single configurations of DNA bases A, C, T, and G have significantly different charge conductance characteristics. This result is consistent with the notion that it is possible to read the nucleotide base sequence on an individual DNA heteropolymer which is moving through a gap between electrically biased nanoelectrodes by measuring the changes in the electron-transport conductance.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2007},
month = {Mon Jan 01 00:00:00 EST 2007}
}

Conference:
Other availability
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