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Dual manifold system and method for fluid transfer

Patent ·
OSTI ID:921802

A dual-manifold assembly is provided for the rapid, parallel transfer of liquid reagents from a microtiter plate to a solid state microelectronic device having biological sensors integrated thereon. The assembly includes aspiration and dispense manifolds connected by a plurality of conduits. In operation, the aspiration manifold is actuated such that the aspiration manifold is seated onto an array of reagent-filled wells of the microtiter plate. The wells are pressurized to force reagent through conduits toward the dispense manifold. A pressure pulse provided by a standard ink-jet printhead ejects nanoliter-to-picoliter droplets of reagent through an array of printhead orifices and onto test sites on the surface of the microelectronic device.

Research Organization:
Oak Ridge National Laboratory (ORNL), Oak Ridge, TN
Sponsoring Organization:
United States Department of Energy
DOE Contract Number:
AC05-96OR22464
Assignee:
UT-Battelle, LLC (Oak Ridge, TN)
Patent Number(s):
6,569,687
Application Number:
09/738,821
OSTI ID:
921802
Country of Publication:
United States
Language:
English

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