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Title: Pre-symptomatic Prediction of Illness in Mice Inoculated with Cowpox

Abstract

We describe here research directed towards early (presyndromic) diagnosis of infection. By using a mouse model and a multi-component blood protein diagnostic tool we detected cowpox infection several days in advance of overt symptoms with high accuracy. We provide details of the experimental design and measurement technique and elaborate on the long-range implication of these results.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
920467
Report Number(s):
UCRL-PROC-230270
TRN: US200818%%655
DOE Contract Number:
W-7405-ENG-48
Resource Type:
Conference
Resource Relation:
Conference: Presented at: NATO-Russia ADVANCED RESEARCH WORKSHOP "Commercial and Pre-commercial Cell Detection Technologies for Defence against Bioterror - Technology, Market and Society", Brno, Czech Republic, Sep 03 - Sep 07, 2007
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE; ACCURACY; BLOOD; DESIGN; DETECTION; DIAGNOSIS; FORECASTING; MARKET; MICE; PROTEINS; SYMPTOMS

Citation Formats

Kercher, J R, Colston, Jr., B W, Langlois, R G, Lyons, C R, and Milanovich, F P. Pre-symptomatic Prediction of Illness in Mice Inoculated with Cowpox. United States: N. p., 2007. Web.
Kercher, J R, Colston, Jr., B W, Langlois, R G, Lyons, C R, & Milanovich, F P. Pre-symptomatic Prediction of Illness in Mice Inoculated with Cowpox. United States.
Kercher, J R, Colston, Jr., B W, Langlois, R G, Lyons, C R, and Milanovich, F P. Thu . "Pre-symptomatic Prediction of Illness in Mice Inoculated with Cowpox". United States. doi:. https://www.osti.gov/servlets/purl/920467.
@article{osti_920467,
title = {Pre-symptomatic Prediction of Illness in Mice Inoculated with Cowpox},
author = {Kercher, J R and Colston, Jr., B W and Langlois, R G and Lyons, C R and Milanovich, F P},
abstractNote = {We describe here research directed towards early (presyndromic) diagnosis of infection. By using a mouse model and a multi-component blood protein diagnostic tool we detected cowpox infection several days in advance of overt symptoms with high accuracy. We provide details of the experimental design and measurement technique and elaborate on the long-range implication of these results.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Apr 19 00:00:00 EDT 2007},
month = {Thu Apr 19 00:00:00 EDT 2007}
}

Conference:
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