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Non-planar microfabricated gas chromatography column

Patent ·
OSTI ID:916926

A non-planar microfabricated gas chromatography column comprises a planar substrate having a plurality of through holes, a top lid and a bottom lid bonded to opposite surfaces of the planar substrate, and inlet and outlet ports for injection of a sample gas and elution of separated analytes. A plurality of such planar substrates can be aligned and stacked to provide a longer column length having a small footprint. Furthermore, two or more separate channels can enable multi-channel or multi-dimensional gas chromatography. The through holes preferably have a circular cross section and can be coated with a stationary phase material or packed with a porous packing material. Importantly, uniform stationary phase coatings can be obtained and band broadening can be minimized with the circular channels. A heating or cooling element can be disposed on at least one of the lids to enable temperature programming of the column.

Research Organization:
Sandia National Laboratories (SNL-NM), Albuquerque, NM
Sponsoring Organization:
United States Department of Energy
DOE Contract Number:
AC04-94AL85000
Assignee:
Sandia Corporation (Albuquerque, NM)
Patent Number(s):
7,273,517
Application Number:
11/067,107
OSTI ID:
916926
Country of Publication:
United States
Language:
English

References (5)

Hand-Held Miniature Chemical Analysis System (μChemlab) for Detection of Trace Concentrations of Gas Phase Analytes book January 2000
Height Equivalent to a Theoretical Plate Theory for Rectangular GC Columns journal November 1998
Microfabricated silicon gas chromatographic microchannels: fabrication and performance conference August 1998
Design, Fabrication, and Evaluation of Microfabricated Columns for Gas Chromatography journal May 2004
Relationships for modeling the performance of rectangular gas chromatographic columns journal January 2001