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Title: Squid detected NMR and MRI at ultralow fields

Abstract

Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.

Inventors:
 [1];  [2];  [1];  [3]
  1. Berkeley, CA
  2. Louisville, CO
  3. CH-8006 Zurich, CH
Publication Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
909400
Patent Number(s):
7,218,104
Assignee:
Clarke, John (Berkeley, CA); McDermott, Robert (Louisville, CO); Pines, Alexander (Berkeley, CA); Trabesinger, Andreas Heinz (CH-8006 Zurich, CH)
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY

Citation Formats

Clarke, John, McDermott, Robert, Pines, Alexander, and Trabesinger, Andreas Heinz. Squid detected NMR and MRI at ultralow fields. United States: N. p., 2007. Web.
Clarke, John, McDermott, Robert, Pines, Alexander, & Trabesinger, Andreas Heinz. Squid detected NMR and MRI at ultralow fields. United States.
Clarke, John, McDermott, Robert, Pines, Alexander, and Trabesinger, Andreas Heinz. 2007. "Squid detected NMR and MRI at ultralow fields". United States. https://www.osti.gov/servlets/purl/909400.
@article{osti_909400,
title = {Squid detected NMR and MRI at ultralow fields},
author = {Clarke, John and McDermott, Robert and Pines, Alexander and Trabesinger, Andreas Heinz},
abstractNote = {Nuclear magnetic resonance (NMR) signals are detected in microtesla fields. Prepolarization in millitesla fields is followed by detection with an untuned dc superconducting quantum interference device (SQUID) magnetometer. Because the sensitivity of the SQUID is frequency independent, both signal-to-noise ratio (SNR) and spectral resolution are enhanced by detecting the NMR signal in extremely low magnetic fields, where the NMR lines become very narrow even for grossly inhomogeneous measurement fields. MRI in ultralow magnetic field is based on the NMR at ultralow fields. Gradient magnetic fields are applied, and images are constructed from the detected NMR signals.},
doi = {},
url = {https://www.osti.gov/biblio/909400}, journal = {},
number = ,
volume = ,
place = {United States},
year = {2007},
month = {5}
}