Near-infrared spectroscopic tissue imaging for medical applications

Demos, Stavros; Staggs, Michael C.

Title: Near-infrared spectroscopic tissue imaging for medical applications

Patent · Tue Mar 21 00:00:00 EST 2006

OSTI ID:908548

Demos, Stavros; Staggs, Michael C.

Near infrared imaging using elastic light scattering and tissue autofluorescence are explored for medical applications. The approach involves imaging using cross-polarized elastic light scattering and tissue autofluorescence in the Near Infra-Red (NIR) coupled with image processing and inter-image operations to differentiate human tissue components.

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Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: W-7405-ENG-48

Assignee:: The Regents of the University of California (Oakland, CA)

Patent Number(s):: 7,016,717

Application Number:: 10/190,231

OSTI ID:: 908548

Country of Publication:: United States

Language:: English

References (8)

Tissue imaging for cancer detection using NIR autofluorescence Demos, Stavros G.; Staggs, Michael C.; Gandour-Edwards, Regina Proc. SPIE, Vol. 4613 https://doi.org/10.1117/12.465260	conference	May 2002
Autofluorescence characteristics of immortalized and carcinogen-transformed human bronchial epithelial cells Pitts, Jonathan D.; Sloboda, Roger D.; Dragnev, Konstantin H. Journal of Biomedical Optics, Vol. 6, Issue 1, p. 31-41 https://doi.org/10.1117/1.1333057	journal	January 2001
Laser induced fluorescence spectroscopy from native cancerous and normal tissue Alfano, R.; Tata, D.; Cordero, J. IEEE Journal of Quantum Electronics, Vol. 20, Issue 12, p. 1507-1511 https://doi.org/10.1109/JQE.1984.1072322	journal	December 1984
<title>Subsurface imaging using the spectral polarization difference technique and NIR illumination</title> Demos, Stavros G.; Radousky, Harry B.; Alfano, Robert R. Proc. SPIE, Vol. 3597 https://doi.org/10.1117/12.356824	conference	July 1999
Aberrant porphyrin metabolism in hepatocellular carcinoma Udagawa, Misako; Horie, Yutaka; Hirayama, Chisato Biochemical Medicine, Vol. 31, Issue 2, p. 131-139 https://doi.org/10.1016/0006-2944(84)90018-8	journal	April 1984
Spectroscopic Diagnosis Of Colonic Dysplasia Richards-Kortum, R.; Rava, R. P.; Petras, R. E. Photochemistry and Photobiology, Vol. 53, Issue 6, p. 777-786 https://doi.org/10.1111/j.1751-1097.1991.tb09892.x	journal	June 1991
Ultraviolet laser-induced fluorescence of colonic tissue: Basic biology and diagnostic potential Schomacker, Kevin T.; Frisoli, Joan K.; Compton, Carolyn C. Lasers in Surgery and Medicine, Vol. 12, Issue 1 https://doi.org/10.1002/lsm.1900120111	journal	January 1992
Destruction of erythroleukaemic cells by photoactivation of endogenous porphyrins Malik, Z.; Lugaci, H. British Journal of Cancer, Vol. 56, Issue 5 https://doi.org/10.1038/bjc.1987.246	journal	November 1987

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