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Title: Image Reconstruction for Prostate Specific Nuclear Medicine imagers

Abstract

There is increasing interest in the design and construction of nuclear medicine detectors for dedicated prostate imaging. These include detectors designed for imaging the biodistribution of radiopharmaceuticals labeled with single gamma as well as positron-emitting radionuclides. New detectors and acquisition geometries present challenges and opportunities for image reconstruction. In this contribution various strategies for image reconstruction for these special purpose imagers are reviewed. Iterative statistical algorithms provide a framework for reconstructing prostate images from a wide variety of detectors and acquisition geometries for PET and SPECT. The key to their success is modeling the physics of photon transport and data acquisition and the Poisson statistics of nuclear decay. Analytic image reconstruction methods can be fast and are useful for favorable acquisition geometries. Future perspectives on algorithm development and data analysis for prostate imaging are presented.

Authors:
Publication Date:
Research Org.:
Thomas Jefferson National Accelerator Facility, Newport News, VA
Sponsoring Org.:
USDOE - Office of Energy Research (ER)
OSTI Identifier:
897365
Report Number(s):
JLAB-PHY-07-607; DOE/OR/23177-0004
TRN: US0701401
DOE Contract Number:
AC05-06OR23177
Resource Type:
Journal Article
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ALGORITHMS; CONSTRUCTION; DATA ACQUISITION; DATA ANALYSIS; DESIGN; NUCLEAR DECAY; NUCLEAR MEDICINE; PHOTON TRANSPORT; PHYSICS; PROSTATE; RADIOISOTOPES; RADIOPHARMACEUTICALS; SIMULATION; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; STATISTICS

Citation Formats

Mark Smith. Image Reconstruction for Prostate Specific Nuclear Medicine imagers. United States: N. p., 2007. Web.
Mark Smith. Image Reconstruction for Prostate Specific Nuclear Medicine imagers. United States.
Mark Smith. Thu . "Image Reconstruction for Prostate Specific Nuclear Medicine imagers". United States. doi:. https://www.osti.gov/servlets/purl/897365.
@article{osti_897365,
title = {Image Reconstruction for Prostate Specific Nuclear Medicine imagers},
author = {Mark Smith},
abstractNote = {There is increasing interest in the design and construction of nuclear medicine detectors for dedicated prostate imaging. These include detectors designed for imaging the biodistribution of radiopharmaceuticals labeled with single gamma as well as positron-emitting radionuclides. New detectors and acquisition geometries present challenges and opportunities for image reconstruction. In this contribution various strategies for image reconstruction for these special purpose imagers are reviewed. Iterative statistical algorithms provide a framework for reconstructing prostate images from a wide variety of detectors and acquisition geometries for PET and SPECT. The key to their success is modeling the physics of photon transport and data acquisition and the Poisson statistics of nuclear decay. Analytic image reconstruction methods can be fast and are useful for favorable acquisition geometries. Future perspectives on algorithm development and data analysis for prostate imaging are presented.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Thu Jan 11 00:00:00 EST 2007},
month = {Thu Jan 11 00:00:00 EST 2007}
}