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Title: Shape Memory Polymer Therapeutic Devices for Stroke

Abstract

Shape memory polymers (SMPs) are attracting a great deal of interest in the scientific community for their use in applications ranging from light weight structures in space to micro-actuators in MEMS devices. These relatively new materials can be formed into a primary shape, reformed into a stable secondary shape, and then controllably actuated to recover their primary shape. The first part of this presentation will be a brief review of the types of polymeric structures which give rise to shape memory behavior in the context of new shape memory polymers with highly regular network structures recently developed at LLNL for biomedical devices. These new urethane SMPs have improved optical and physical properties relative to commercial SMPs, including improved clarity, high actuation force, and sharper actuation transition. In the second part of the presentation we discuss the development of SMP based devices for mechanically removing neurovascular occlusions which result in ischemic stroke. These devices are delivered to the site of the occlusion in compressed form, are pushed through the occlusion, actuated (usually optically) to take on an expanded conformation, and then used to dislodge and grip the thrombus while it is withdrawn through the catheter.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
885377
Report Number(s):
UCRL-PROC-216091
Journal ID: ISSN 0277-786X; TRN: US200616%%586
DOE Contract Number:  
W-7405-ENG-48
Resource Type:
Conference
Resource Relation:
Journal Volume: 6007; Conference: Presented at: SPIE Optics East, Boston, MA, United States, Oct 23 - Oct 26, 2005
Country of Publication:
United States
Language:
English
Subject:
36 MATERIALS SCIENCE; 47 OTHER INSTRUMENTATION; 71 CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS; 37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; LAWRENCE LIVERMORE NATIONAL LABORATORY; OPTICS; PHYSICAL PROPERTIES; POLYMERS; SHAPE; URETHANE

Citation Formats

Wilson, T S, Small, IV, W, Benett, W J, Bearinger, J P, and Maitland, D J. Shape Memory Polymer Therapeutic Devices for Stroke. United States: N. p., 2005. Web. doi:10.1117/12.630873.
Wilson, T S, Small, IV, W, Benett, W J, Bearinger, J P, & Maitland, D J. Shape Memory Polymer Therapeutic Devices for Stroke. United States. https://doi.org/10.1117/12.630873
Wilson, T S, Small, IV, W, Benett, W J, Bearinger, J P, and Maitland, D J. Tue . "Shape Memory Polymer Therapeutic Devices for Stroke". United States. https://doi.org/10.1117/12.630873. https://www.osti.gov/servlets/purl/885377.
@article{osti_885377,
title = {Shape Memory Polymer Therapeutic Devices for Stroke},
author = {Wilson, T S and Small, IV, W and Benett, W J and Bearinger, J P and Maitland, D J},
abstractNote = {Shape memory polymers (SMPs) are attracting a great deal of interest in the scientific community for their use in applications ranging from light weight structures in space to micro-actuators in MEMS devices. These relatively new materials can be formed into a primary shape, reformed into a stable secondary shape, and then controllably actuated to recover their primary shape. The first part of this presentation will be a brief review of the types of polymeric structures which give rise to shape memory behavior in the context of new shape memory polymers with highly regular network structures recently developed at LLNL for biomedical devices. These new urethane SMPs have improved optical and physical properties relative to commercial SMPs, including improved clarity, high actuation force, and sharper actuation transition. In the second part of the presentation we discuss the development of SMP based devices for mechanically removing neurovascular occlusions which result in ischemic stroke. These devices are delivered to the site of the occlusion in compressed form, are pushed through the occlusion, actuated (usually optically) to take on an expanded conformation, and then used to dislodge and grip the thrombus while it is withdrawn through the catheter.},
doi = {10.1117/12.630873},
url = {https://www.osti.gov/biblio/885377}, journal = {},
issn = {0277-786X},
number = ,
volume = 6007,
place = {United States},
year = {2005},
month = {10}
}

Conference:
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