Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Sol-Gel Matrices For Direct Colorimetric Detection Of Analytes

Patent ·
OSTI ID:879643
The present invention relates to methods and compositions for the direct detection of analytes using color changes that occur in immobilized biopolymeric material in response to selective binding of analytes to their surface. In particular, the present invention provides methods and compositions related to the encapsulation of biopolymeric material into metal oxide glass using the sol-gel method.
Research Organization:
SANDIA CORP
DOE Contract Number:
AC04-94AL85000
Assignee:
Regents of the University of California (Oakland, CA); Sandia Corporation (NM)
Patent Number(s):
US 6485987
Application Number:
09/500,295
OSTI ID:
879643
Country of Publication:
United States
Language:
English

References (51)

Molecular Recognition and Colorimetric Detection of Cholera Toxin by Poly(diacetylene) Liposomes Incorporating G m1 Ganglioside journal March 1997
Optical detection of toxic gases using fluorescent porphyrin langumuir—blodgett films journal July 1988
Polydiacetylene Liposomes Functionalized with Sialic Acid Bind and Colorimetrically Detect Influenza Virus journal January 1995
Amperometric Glucose Sensor with Glucose Oxidase Immobilized on SnO 2 Electrode via a Monolayer of a Photoreactive Nitrophenylazide Derivative journal April 1990
Epidermal growth factor receptor occupancy inhibits vaccinia virus infection journal December 1985
Atomic Resolution with Atomic Force Microscope journal June 1987
Monoclonal antibody identification of a 100-kDa membrane protein in HeLa cells and human spinal cord involved in poliovirus attachment. journal October 1988
Morphology of Crystalline Diacetylene Monolayers Polymerized at the Gas-Water Interface journal November 1980
Hybrid gas detector of squarylium dye Langmuir-Blodgett film deposited on a quartz oscillator journal April 1992
Atomic Force Microscope journal March 1986
Fibroblast growth factor receptor is a portal of cellular entry for herpes simplex virus type 1 journal June 1990
Viral receptors of the immunoglobulin superfamily journal March 1989
Direct colorimetric detection of a receptor-ligand interaction by a polymerized bilayer assembly journal July 1993
Spatially Resolved Mineral Deposition on Patterned Self-Assembled Monolayers journal March 1994
A soluble form of intercellular adhesion molecule-1 inhibits rhinovirus infection journal March 1990
Biosensors for Measuring Pesticide Residues in the Environment: Past, Present, and Future journal November 1996
Thermal desorption-gas chromatography-mass spectrometry-flame ionization detection-sniffer multi-coupling: A device for the determination of odorous volatile organic compounds in air journal July 1995
Absorption properties and structure changes caused by pre-annealing in polydiacetylene Langmuir-Blodgett films journal April 1992
Atomic force microscopy imaging of T4 bacteriophages on silicon substrates journal July 1992
Vasoactive intestinal peptide 1-12: A ligand for the CD4 (T4)/human immunodeficiency virus receptor journal January 1987
Cellular receptor for poliovirus: Molecular cloning, nucleotide sequence, and expression of a new member of the immunoglobulin superfamily journal March 1989
Structural requirements for C3d,g/Epstein-Barr virus receptor (CR2/CD21) ligand binding, internalization, and viral infection. journal July 1990
Synthesis conditions for encapsulating cytochrome c and catalase in SiO2 sol-gel materials journal July 1996
CD4 receptor binding peptides that block HIV infectivity cause human monocyte chemotaxis: Relationship to vasoactive intestinal polypeptide journal January 1987
Reversible colour phase transitions and annealing properties of Langmuir-Blodgett polydiacetylene films journal November 1989
Characterization of octyl glucoside-solubilized cell membrane receptors for binding measles virus journal September 1989
Influence of biotin lipid surface density and accessibility on avidin binding to the tip of an optical fiber sensor journal November 1992
Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid journal June 1988
Nicotinamide Adenine Dinucleotide Phosphate Fluorescence and Absorption Monitoring of Enzymic Activity in Silicate Sol-Gels for Chemical Sensing Applications journal September 1995
A selective SAW-based organophosphonate chemical sensor employing a self-assembled, composite monolayer: a new paradigm for sensor design journal December 1992
Formation of stable monolayer membranes and related structures in dilute aqueous solution from two-headed ammonium amphiphiles journal August 1979
Encapsulation of proteins in transparent porous silicate glasses prepared by the sol-gel method journal February 1992
Interactions of Animal Viruses with Cell Surface Receptors book January 1985
Monitoring a dryer operation using an array of piezoelectric crystals journal March 1988
Monomolecular Langmuir-Blodgett films at electrodes. Formation of passivating monolayers and incorporation of electroactive reagents journal November 1991
Entry of genital Chlamydia trachomatis into polarized human epithelial cells. journal January 1989
Biosensors journal August 1984
Isolation and biochemical characterization of the mammalian reovirus type 3 cell-surface receptor. journal March 1985
Specific Interaction of Influenza Virus with Organized Assemblies of Polydiacetylenes journal January 1992
Imaging of polydiacetylene on graphite by scanning tunneling microscopy journal February 1991
Detection of hazardous vapors including mixtures using pattern recognition analysis of responses from surface acoustic wave devices journal December 1988
Lipids and Minerals Form Novel Composite Microstructures: Variety of shapes and compositions possible by varying organic, inorganic ingredients and reaction conditions journal August 1993
The optical activity and circular dichroic spectra of diacetylenic phospholipid polymers journal December 1982
Sol-gel encapsulation methods for biosensors journal November 1994
Atomic force microscope study of chromatic transitions in polydiacetylene thin films journal March 1996
Organic Chemistry within Ceramic Matrixes: Doped Sol-Gel Materials journal August 1995
Is the acetylcholine receptor a rabies virus receptor? journal January 1982
Multivariate sensor arrays as industrial and environmental monitoring systems journal May 1994
Identification of a putative cell receptor for human cytomegalovirus journal June 1990
Polymerized liposomes containing C-glycosides of sialic acid: potent inhibitors of influenza virus in vitro infectivity journal February 1993
Solid Phase Immobilization of Optically Responsive Liposomes in Sol-Gel Materials for Chemical and Biological Sensing journal September 1997

Similar Records

Related Subjects