Flowmeter for pressure-driven chromatography systems
- Livermore, CA
A flowmeter for accurately measuring the flowrate of fluids in high pressure chromatography systems. The flowmeter is a porous bed of a material, the porous bed having a porosity in the range of about 0.1 to 0.6 and a pore size in the range of about 50 nm to 1 .mu.m, disposed between a high pressure pumping means and a chromatography column. The flowmeter is provided with pressure measuring means at both the inlet and outlet of the porous bed for measuring the pressure drop through the porous bed. This flowmeter system provides not only the ability to measure accurately flowrates in the range of .mu.L/min to nL/min but also to provide a signal that can be used for a servo loop or feedback control system for high pressure pumping systems.
- Research Organization:
- Sandia National Laboratories (SNL), Albuquerque, NM, and Livermore, CA (United States)
- DOE Contract Number:
- AC04-94AL85000
- Assignee:
- Sandia National Laboratories (Livermore, CA)
- Patent Number(s):
- US 6532802
- OSTI ID:
- 875105
- Country of Publication:
- United States
- Language:
- English
Similar Records
Sample preparation system for microfluidic applications
High-pressure microhydraulic actuator
Related Subjects
pressure-driven
chromatography
systems
accurately
measuring
flowrate
fluids
pressure
porous
bed
material
porosity
range
01
06
pore
size
50
nm
mum
disposed
pumping
means
column
provided
inlet
outlet
drop
provides
ability
measure
flowrates
mulmin
nlmin
provide
signal
servo
loop
feedback
control
pore size
chromatography column
pressure pump
porous bed
/73/210/