Electrochemical methods for generation of a biological proton motive force and pyridine nucleotide cofactor regeneration

Patent · Tue Jan 01 00:00:00 EST 2002

OSTI ID:874944

Zeikus, Gregory J ^[1]; Shin, Hyoun S ^[2]; Jain, Mahendra K ^[3]

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1. Okemos, MI
2. Lansing, MI
3. Lexington, KY

Disclosed are methods using neutral red to mediate the interconversion of chemical and electrical energy. Electrically reduced neutral red has been found to promote cell growth and formation of reduced products by reversibly increasing the ratio of the reduced:oxidized forms of NAD(H) or NADP(H). Electrically reduced neutral red is able to serve as the sole source of reducing power for microbial, cell growth. Neutral red is also able to promote conversion of chemical energy to electrical energy by facilitating the transfer of electrons from microbial reducing power to a fuel cell cathode.

• Research Organization: Michigan State University (East Lansing, MI)
• DOE Contract Number: FG02-93ER20108
• Assignee: Michigan State University (East Lansing, MI)
• Patent Number(s): US 6495023
• OSTI ID: 874944
• Country of Publication: United States
• Language: English

Related Subjects

electrochemical
methods
generation
biological
proton
motive
force
pyridine
nucleotide
cofactor
regeneration
disclosed
neutral
mediate
interconversion
chemical
electrical
energy
electrically
reduced
found
promote
cell
growth
formation
products
reversibly
increasing
ratio
reducedoxidized
forms
nadh
nadph
serve
sole
source
reducing
power
microbial
conversion
facilitating
transfer
electrons
fuel
cathode
fuel cell
electrical energy
chemical energy
electrochemical method
motive force
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