Dual mode stereotactic localization method and application

Patent · Tue Jan 01 00:00:00 EST 2002

OSTI ID:874440

Keppel, Cynthia E ^[1]; Barbosa, Fernando Jorge ^[2]; Majewski, Stanislaw ^[3]

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1. Norfolk, VA
2. Newport News, VA
3. Grafton, VA

The invention described herein combines the structural digital X-ray image provided by conventional stereotactic core biopsy instruments with the additional functional metabolic gamma imaging obtained with a dedicated compact gamma imaging mini-camera. Before the procedure, the patient is injected with an appropriate radiopharmaceutical. The radiopharmaceutical uptake distribution within the breast under compression in a conventional examination table expressed by the intensity of gamma emissions is obtained for comparison (co-registration) with the digital mammography (X-ray) image. This dual modality mode of operation greatly increases the functionality of existing stereotactic biopsy devices by yielding a much smaller number of false positives than would be produced using X-ray images alone. The ability to obtain both the X-ray mammographic image and the nuclear-based medicine gamma image using a single device is made possible largely through the use of a novel, small and movable gamma imaging camera that permits its incorporation into the same table or system as that currently utilized to obtain X-ray based mammographic images for localization of lesions.

• Research Organization: Southeastern Universities Research Associations (SURA), Washington, DC (United States)
• DOE Contract Number: AC05-84ER40150
• Assignee: Southeastern Universities Research Assn., Inc. (Newport News, VA)
• Patent Number(s): US 6389098
• OSTI ID: 874440
• Country of Publication: United States
• Language: English

Related Subjects

dual
mode
stereotactic
localization
method
application
described
combines
structural
digital
x-ray
image
provided
conventional
core
biopsy
instruments
additional
functional
metabolic
gamma
imaging
obtained
dedicated
compact
mini-camera
procedure
patient
injected
appropriate
radiopharmaceutical
uptake
distribution
breast
compression
examination
expressed
intensity
emissions
comparison
co-registration
mammography
modality
operation
greatly
increases
functionality
existing
devices
yielding
false
positives
produced
images
ability
obtain
mammographic
nuclear-based
medicine
single
device
novel
movable
camera
permits
incorporation
currently
utilized
based
lesions
x-ray image
/378/250/