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Title: Hybridization and sequencing of nucleic acids using base pair mismatches

Abstract

Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques.

Inventors:
 [1];  [1];  [2]
  1. (Palo Alto, CA)
  2. (Mt. View, CA)
Publication Date:
Research Org.:
Affymax Research Institute
OSTI Identifier:
873966
Patent Number(s):
US 6284460
Assignee:
Affymetrix Inc. (Santa Clara, CA) OAK
DOE Contract Number:  
FG03-92ER81275
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
hybridization; sequencing; nucleic; acids; base; pair; mismatches; devices; techniques; determining; sequence; arrays; formed; preferably; resolution; light-directed; positions; target; acid; determined; epifluorescence; microscopy; proposed; determine; efficiently; quickly; synthesis; detection; detection techniques; nucleic acid; nucleic acids; target nucleic; base pair; epifluorescence microscopy; light-directed techniques; target nuclei; /435/999/

Citation Formats

Fodor, Stephen P. A., Lipshutz, Robert J., and Huang, Xiaohua. Hybridization and sequencing of nucleic acids using base pair mismatches. United States: N. p., 2001. Web.
Fodor, Stephen P. A., Lipshutz, Robert J., & Huang, Xiaohua. Hybridization and sequencing of nucleic acids using base pair mismatches. United States.
Fodor, Stephen P. A., Lipshutz, Robert J., and Huang, Xiaohua. Mon . "Hybridization and sequencing of nucleic acids using base pair mismatches". United States. https://www.osti.gov/servlets/purl/873966.
@article{osti_873966,
title = {Hybridization and sequencing of nucleic acids using base pair mismatches},
author = {Fodor, Stephen P. A. and Lipshutz, Robert J. and Huang, Xiaohua},
abstractNote = {Devices and techniques for hybridization of nucleic acids and for determining the sequence of nucleic acids. Arrays of nucleic acids are formed by techniques, preferably high resolution, light-directed techniques. Positions of hybridization of a target nucleic acid are determined by, e.g., epifluorescence microscopy. Devices and techniques are proposed to determine the sequence of a target nucleic acid more efficiently and more quickly through such synthesis and detection techniques.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2001},
month = {1}
}

Patent:

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